Results 111 to 120 of about 8,256,465 (313)

The Study of Geomechanical Condition of Unstable Rocks in the Vicinity of Mine Working Junctions

Горные науки и технологии, 2019
The relevance of research of material strain nature based on physical models equivalent to rocks is substantiated. To identify the dependencies and mechanism of unstable rock strain in the vicinity of mine working junctions, an experimental technique has
V. V. Basov
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Diffusely scattered and transmitted elastic waves by random rough solid-solid interfaces using an elastodynamic Kirchhoff approximation [PDF]

, 2017
Elastic waves scattered by random rough interfaces separating two distinct media play an important role in modeling phonon scattering and impact upon thermal transport models, and are also integral to ultrasonic inspection.
Shi, F, Lowe, M, Mike Lowe, Craster, R, Shi, Fan, Lowe, Mike, Richard Craster, Craster, Richard, Fan Shi   +8 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Scattering spectra models for physics

PNAS Nexus
Abstract Physicists routinely need probabilistic models for a number of tasks such as parameter inference or the generation of new realizations of a field. Establishing such models for highly non-Gaussian fields is a challenge, especially when the number of samples is limited.
Sihao Cheng, Rudy Morel, Erwan Allys, Brice Ménard, Stéphane Mallat   +4 more
openaire   +4 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

A Physical Model of the Reeb Foliation

Axioms
In this paper, after explaining some basic aspects of the modern theory of foliations with the aim of describing the celebrated Reeb foliation, we propose the first construction of a comprehensive physical model of it. The construction of the model is achieved through an implementation of geometric methods for 3D printing.
Bande, Gianluca, Franzoni, Gregorio
openaire   +2 more sources

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Physical modeling supporting a storyline approach [PDF]

, 2019
The concept of analyzing and communicating high-impact events in the climate change context via storylines has recently gained popularity in the climate modeling community. For instance, the use of case studies or storylines that could illustrate climate
Zscheischler, Jakob, van den Hurk, Bart, Sillmann, Jana, Shepherd, Ted, Hurk, Bart van den, Martius, Olivia, Hazeleger, Wilco   +6 more
core   +1 more source