Results 181 to 190 of about 8,811,391 (311)

Crack-Resistant Cements under Drying: Results from Ring Shrinkage Tests and Multi-Physical Modeling. [PDF]

Materials (Basel), 2022
Šmilauer V, Reiterman P, Šulc R, Schořík P.   +3 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

A prediction tool for plaque progression based on patient-specific multi-physical modeling. [PDF]

PLoS Comput Biol, 2021
Pan J, Cai Y, Wang L, Maehara A, Mintz GS, Tang D, Li Z.   +6 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Mesoscale meteorological modeling /

The 3rd edition of Mesoscale Meteorological Modeling is a fully revised resource for researchers and practitioners in the growing field of meteorological modeling at the mesoscale.
Pielke, Roger A.Sr.,author.
core  

Block-Based Physical Modeling for Digital Sound Synthesis

, 2008
Block-based physical modeling is a methodology for modeling physical systems with different subsystems. It is an important concept for the physical modeling of real or virtual musical instruments where different components may be modeled according to ...

core  

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

An Integrative Approach to Determine 3D Protein Structures Using Sparse Paramagnetic NMR Data and Physical Modeling. [PDF]

Front Mol Biosci, 2021
Gaalswyk K, Liu Z, Vogel HJ, MacCallum JL.   +3 more
europepmc   +1 more source

Physical and phenomenological modeling of automotive LiDAR sensors for real-time applications

PHYSICAL AND PHENOMENOLOGICAL MODELING OF AUTOMOTIVE LIDAR SENSORS FOR REAL-TIME APPLICATIONS Physical and phenomenological modeling of automotive LiDAR sensors for real-time applications / Chen, Haopeng (Rights reserved) (-
Chen, Haopeng
core  

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source