Results 111 to 120 of about 8,811,391 (311)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Blind Separation of Skin Chromophores from Multispectral Dermatological Images

open access: yesDiagnostics
Background/Objectives: Based on Blind Source Separation and the use of multispectral imaging, the new approach we propose in this paper aims to improve the estimation of the concentrations of the main skin chromophores (melanin, oxyhemoglobin and ...
Mustapha Zokay, Hicham Saylani
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Physical system modeling with Modelica

open access: yes, 1998
A new language Modelica, for the modeling of physical systems has been developed in an international effort. The main objective was to make it easy to exchange models and model libraries.
Sven Erik Mattsson   +5 more
core   +1 more source

Using Rasch modeling to re-evaluate three scales related to physical activity: Enjoyment, perceived benefits and perceived barriers [PDF]

open access: yes, 2006
Studies suggest that enjoyment, perceived benefits and perceived barriers may be important mediators of physical activity. However, the psychometric properties of these scales have not been assessed using Rasch modeling.
Masse, L.C.   +5 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

The Study of Geomechanical Condition of Unstable Rocks in the Vicinity of Mine Working Junctions

open access: yesГорные науки и технологии, 2019
The relevance of research of material strain nature based on physical models equivalent to rocks is substantiated. To identify the dependencies and mechanism of unstable rock strain in the vicinity of mine working junctions, an experimental technique has
V. V. Basov
doaj   +1 more source

Physical modeling versus numerical modeling

open access: yes, 2003
Despite the widespread use of numerical modeling, there is still room for physical modeling today for many reasons. E.g., physical modeling is based on real wave propagation whereas numerical modeling is based on algorithms which are by necessity ...
Veldhuizen, E. van, Blacquière, G.
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

The evolution of a polydisperse ensemble of ellipsoidal particles in the form of prolate and oblate ellipsoids of revolution

open access: yesResults in Physics
The evolution of a polydisperse ensemble of prolate and oblate ellipsoidal crystals in a supercooled one-component melt is theoretically studied. The volume growth rates for prolate and oblate ellipsoids are analytically found and compared at the same ...
Dmitri V. Alexandrov   +4 more
doaj   +1 more source

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