FROM QUANTUM PHYSICS TO PHYSICAL MODELS
Romanian Journal of Neurology, 2017 As regards the issue of complexity, human brain is one of the most complex systems we know. The study of neural networks, their relation to the operation of single neurons and other important topics do and will profit a lot from complex systems approaches.
Gabriel Crumpei +2 more
openaire +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Numerical and Physical Modeling of Liquid Steel Asymmetric Behavior during Non-Isothermal Conditions in a Two-Strand Slab Tundish-"Butterfly Effect". [PDF]
Materials (Basel), 2023 Cwudziński A, Pieprzyca J, Merder T.
europepmc +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Physical modeling and geometric shape simulation for one-dimensional flexible objects with cylindrical surface constraints. [PDF]
Sci Rep, 2023 Mei Y, Du H, Jiang Q, Xiong W.
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Physical modeling of ribosomes along messenger RNA: Estimating kinetic parameters from ribosome profiling experiments using a ballistic model. [PDF]
PLoS Comput Biol, 2023 Chevalier C +11 more
europepmc +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Physical Modeling of the Impeller Construction Impact on the Aluminum Refining Process. [PDF]
Materials (Basel), 2022 Saternus M, Merder T.
europepmc +1 more source
Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller +6 more
wiley +1 more source