Results 111 to 120 of about 459,731 (269)

Physical modeling of ribosomes along messenger RNA: Estimating kinetic parameters from ribosome profiling experiments using a ballistic model. [PDF]

PLoS Comput Biol, 2023
Chevalier C, Dorignac J, Ibrahim Y, Choquet A, David A, Ripoll J, Rivals E, Geniet F, Walliser NO, Palmeri J, Parmeggiani A, Walter JC.   +11 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Experimental and Numerical Study of Tension Bearing Capacity of Circular Skirted Foundations Resting on Sand Bed

نشریه مهندسی دریا, 2019
Skirted foundations are an appropriate alternative to deep foundations in onshore and offshore structures, which have the ability to withstand uplift loads, are also easy to be installed. The tensile performance of skirted foundations on sand was studied
Sajjad Gholipour, Masoud Makarchian
doaj  

Inception of Constructional Submarine Conduit by Asymmetry Generated by Turbidity Current

Journal of Marine Science and Engineering
Submarine conduits are features responsible for transporting clastic debris from continents to the deep ocean. While the architecture of conduits has been extensively studied, the process of their inception remains unclear.
Daniel Bayer da Silva, Eduardo Puhl, Rafael Manica, Ana Luiza de Oliveira Borges, Adriano Roessler Viana   +4 more
doaj   +1 more source

Physical Modeling of the Impeller Construction Impact on the Aluminum Refining Process. [PDF]

Materials (Basel), 2022
Saternus M, Merder T.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Development of Preliminary Precision Forging Technology and Concept for Tools Used to Reforge 60E1A6 Profile Needle Rails with the Use of Numerical and Physical Modeling. [PDF]

Materials (Basel), 2023
Hawryluk M, Cygan P, Krawczyk J, Barełkowski A, Ziemba J, Lewandowski F, Wieczorek I.   +6 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Integrated Physical Modeling and Optimal Control Method of Limited-Angle Torque Motor in Fuel Metering Apparatus. [PDF]

Micromachines (Basel), 2022
Chen Q, Sheng H, Jiang S.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source