Results 151 to 160 of about 581,628 (317)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Affordance-based Design of Physical Interfaces for Ubiquitous Computing Environments [PDF]

open access: yes, 2005
Physical interfaces have been proposed as a way to realize natural interactions with ubiquitous computing environments. The successful design of such interfaces requires design approaches that integrate aspects of our world which are usually treated ...
Gerd Kortuem   +3 more
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Validation of Erosion Modeling: Physical and Numerical

open access: yes, 2012
The overall intent of this research is to develop numerical models of erosion of levees, dams and embankments, validated by physical models. The physical models are performed at 1-g and at high g\u27s using a geotechnical centrifuge.
Franklin, W. Randolph   +11 more
core   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Correction: A prediction tool for plaque progression based on patient-specific multi-physical modeling. [PDF]

open access: yesPLoS Comput Biol, 2021
Pan J   +6 more
europepmc   +1 more source

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