Results 151 to 160 of about 8,228,052 (313)

Numerical and physical modeling of breast cancer based on image fusion and artificial intelligence. [PDF]

Breast Cancer Res Treat, 2023
Dołęga-Kozierowski B, Kasprzak P, Lis M, Szynglarewicz B, Matkowski R, Sawicki M, Dymek M, Szumiejko A, Carmo G, Kwiatkowski A, Soliński DG, Ptak M.   +11 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Using Physical Modeling to Optimize the Aluminium Refining Process. [PDF]

Materials (Basel), 2022
Prášil T, Socha L, Gryc K, Svizelová J, Saternus M, Merder T, Pieprzyca J, Gráf M.   +7 more
europepmc   +1 more source

White book on physical and rehabilitation medicine (PRM) in Europe. Chapter 7.The clinical field of competence: PRM in practice

, 2018
In the context of the White Book on Physical and Rehabilitation Medicine (PRM) in Europe this paper deals with the scope and competencies of PRM starting from its definition as the "medicine of functioning." PRM uses the rehabilitative health strategy as
Ceravolo Maria Gabriella, European Physical and Rehabilitation Medicine Bodies Alliance   +1 more
core   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

White Book on Physical and Rehabilitation Medicine (PRM) in Europe. Chapter 11. Challenges and perspectives for the future of PRM

, 2018
In the context of the White Book of Physical and Rehabilitation Medicine (PRM) in Europe, this paper deals with the future perspectives of PRM in Europe according to the actual vision of the European Bodies.
Ceravolo Maria Gabriella, European Physical and Rehabilitation Medicine Bodies Alliance.   +1 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Numerical and Physical Modeling of Liquid Steel Asymmetric Behavior during Non-Isothermal Conditions in a Two-Strand Slab Tundish-"Butterfly Effect". [PDF]

Materials (Basel), 2023
Cwudziński A, Pieprzyca J, Merder T.
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Physical modeling and geometric shape simulation for one-dimensional flexible objects with cylindrical surface constraints. [PDF]

Sci Rep, 2023
Mei Y, Du H, Jiang Q, Xiong W.
europepmc   +1 more source