Results 111 to 120 of about 8,224,221 (312)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Blind Separation of Skin Chromophores from Multispectral Dermatological Images
DiagnosticsBackground/Objectives: Based on Blind Source Separation and the use of multispectral imaging, the new approach we propose in this paper aims to improve the estimation of the concentrations of the main skin chromophores (melanin, oxyhemoglobin and ...
Mustapha Zokay, Hicham Saylani
doaj +1 more source
Interharmonics: Theory and Modeling
, 2007 Some of the most remarkable issues related to interharmonic theory and modeling are presented. Starting from the basic definitions and concepts, attention is first devoted to interharmonic sources.
IEEE TASK FORCE ON HARMONICS MODELING a. S. +2 more
core +1 more source
Renormalization group for link percolation on planar hyperbolic manifolds [PDF]
, 2019 Network geometry is currently a topic of growing scientific interest, as it opens the possibility to explore and interpret the interplay between structure and dynamics of complex networks using geometrical arguments.
Mathematical Modeling +7 more
core +2 more sources
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The hunt for canards in population dynamics: A predator-prey system [PDF]
, 2014 Equations with periodic coefficients for singularly perturbed growth can be analysed by using fast and slow timescales which involves slow manifolds, canards and the dynamical exchanges between several slow manifolds.
Mathematical Modeling +2 more
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
University research: From physical modeling to journal paper writing
, 2009 Monday, June 22, 9-13 Fluid Mechanics modeling Motivation Scaling laws Possibilities Limitations Examples Tuesday, June 23 9-13 Scour and impulse waves in hydraulic engineering Issues of scour Plunge pool scour Pier scour Engineering ...
PULCI DORIA, GUELFO
core
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Results in PhysicsThe evolution of a polydisperse ensemble of prolate and oblate ellipsoidal crystals in a supercooled one-component melt is theoretically studied. The volume growth rates for prolate and oblate ellipsoids are analytically found and compared at the same ...
Dmitri V. Alexandrov +4 more
doaj +1 more source