Results 51 to 60 of about 2,350,673 (316)
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Influence of the steeped spillway slope on the number of optimal steps [PDF]
علوم و مهندسی آبیاری, 2010 In the present study 54 step spillways make of ple Glass, 5 discharges (10, 20, 30, 40 and 50 l/s/m) and 3 slopes, z=1.7 , z=2 and z=2.5 (totally 275 experiments were conducted).
Siavash Heydari orojlo +2 more
doaj +1 more source
Two-Scale Investigation of the Retention Behavior of a Well-Graded Mixed Soil
Geosciences, 2021 The hydraulic characterization of mixed compacted soils is helpful for the design of earthworks subjected to drying–wetting cycles. When the mixed soil is well-graded and made of both coarse and fine fractions, its matric suction may also be due to the ...
Osvaldo Bottiglieri +2 more
doaj +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
AgriEngineering, 2023 Modeling and simulation have become fundamental tools for the microclimatic analysis of greenhouses under various climatic conditions. These models allow precise control of the climate inside the structures and the optimization of their performance under
Gloria Alexandra Ortiz +4 more
doaj +1 more source
Modeling IoT-aware Business Processes - A State of the Art Report [PDF]
, 2018 This research report presents an analysis of the state of the art of modeling Internet of Things (IoT)-aware business processes. IOT links the physical world to the digital world. Traditionally, we would find information about events and processes in the
Asensio, E. Serral +4 more
core +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Energies, 2019 Accurate prediction of pollutant dispersion is vital to the energy industry. This study investigated the Computational Fluid Dynamics (CFD) simulation of pollutant emission in a natural draft dry cooling tower (NDDCT) with flue gas injection. In order to
Guangjun Yang +9 more
doaj +1 more source
Predicting Elevated TSH Levels in the Physical Examination Population With a Machine Learning Model [PDF]
, 2022 Xinqi Cheng +10 more
openalex +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source