Results 91 to 100 of about 1,852,356 (316)
Equilibrium dynamics in two-sector models of endogenous growth [PDF]
, 1994 This paper presents an account of the dynamics of endogenous growth models with physical capital and human capital. We consider some important extensions of the basic framework of Lucas (1988) and Uzawa (1964), including physical capital in the human ...
Ladrón de Guevara, Antonio +6 more
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Learning optimal quantum models is NP-hard
, 2018 Physical modeling translates measured data into a physical model. Physical modeling is a major objective in physics and is generally regarded as a creative process. How good are computers at solving this task?
Stark, Cyril, Cyril J. Stark
core +1 more source
Elements of a stochastic 3D prediction engine in larval zebrafish prey capture
eLife, 2019 The computational principles underlying predictive capabilities in animals are poorly understood. Here, we wondered whether predictive models mediating prey capture could be reduced to a simple set of sensorimotor rules performed by a primitive organism.
Andrew D Bolton +7 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Owner-centric sharing of physical resources, data, and data-driven insights in digital ecosystems [PDF]
, 2019 We are living in an age in which digitization will connect more and more physical assets with IT systems and where IoT endpoints will generate a wealth of valuable data.
Kirk, Laurence +5 more
core +1 more source
, 2023 Physical education and sports foster, amplify, and enrich opportunities for experiential learning, while also facilitating interaction and communication with others, enabling expression through diverse means of communication.
Cereda Ferdinando
core +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source