Results 41 to 50 of about 1,876,053 (276)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Similarity Among Physical Phenomena Recognized on the Basis of the Classification of Existing Knowledge

Journal of Mathematical Sciences and Modelling, 2020
This work presents the synthetical mathematical analysis of available knowledge regarding physical phenomena of research interest. The work is not focusing on providing the phenomena according to the physical laws but rather because of them, hence, it is
Antonios Kanavouras, Frank Coutelieris
doaj   +1 more source

Thermodynamically consistent Darcy–Brinkman–Forchheimer framework in matrix acidization★

Oil & Gas Science and Technology, 2021
Matrix acidization is an important technique used to enhance oil production at the tertiary recovery stage, but its numerical simulation has never been verified.
Wu Yuanqing, Kou Jisheng, Sun Shuyu, Wu Yu-Shu   +3 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Catalog of 525 sprites observed over Japan from September 2016 to March 2021

Heliyon, 2023
We present a catalog of 525 sprites detected over the Sea of Japan and a northeast part of the Pacific Ocean from Sagamihara between September 2016 and March 2021. We analyze the morphology of 525, estimate the location of 441, and calculate the accurate
Maomao Duan, Takanori Sakamoto, Teruaki Enoto, Yuuki Wada, Masashi Kamogawa, Koji Ito   +5 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Millisecond Oscillations in X-Ray Binaries [PDF]

, 2000
The first millisecond X-ray variability phenomena from accreting compact objects have recently been discovered with the Rossi X-ray Timing Explorer. Three new phenomena are observed from low-mass X-ray binaries containing low-magnetic-field neutron stars:
Barret D, Barret D, Bildsten L, Bloser PF, Boirin L, Bradt HV, Bulik T, Campana S, Chakrabarty D, Cui W, Datta B, di Salvo T, Dotani T, Einstein A, Ford E, Ford EC, Fox DW, Gilfanov M, Hasinger G, Hasinger G, Homan J, Homan J, Homan J, in 't Zand JJM, Jongert HC, Jonker PG, Karas V, Kuulkers E, Kuulkers E, Kuulkers E, Kuulkers E, Lai D, Lamb FK, Lewin WHG, Livio M, M. van der Klis, Makishima K, Markwardt CB, Marshall FE, Morgan EH, Muno MP, Murakami T, Psaltis D, Psaltis D, Remillard R, Remillard RA, Remillard RA, Shvartsman VF, Smale AP, Strohmayer T, Strohmayer T, Strohmayer TE, Strohmayer TE, Sunyaev RA, Thirring H, Titarchuk L, van der Klis M, van der Klis M, van der Klis M, van der Klis M, van der Klis M, van der Klis M, van Paradijs J, van Straaten S, Wijnands R, Wijnands R, Wijnands RAD, Yoshida K, Zhang W   +68 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Nature as a Network of Morphological Infocomputational Processes for Cognitive Agents [PDF]

, 2017
This paper presents a view of nature as a network of infocomputational agents organized in a dynamical hierarchy of levels. It provides a framework for unification of currently disparate understandings of natural, formal, technical, behavioral and social
Dodig Crnkovic, Gordana
core   +2 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source