Results 41 to 50 of about 302,016 (253)

Multiscale Time-Splitting Strategy for Multiscale Multiphysics Processes of Two-Phase Flow in Fractured Media

open access: yesJournal of Applied Mathematics, 2011
The temporal discretization scheme is one important ingredient of efficient simulator for two-phase flow in the fractured porous media. The application of single-scale temporal scheme is restricted by the rapid changes of the pressure and saturation in ...
Jisheng Kou, Shuyu Sun, Bo Yu
doaj   +1 more source

Thermodynamically consistent modeling of two-phase incompressible flows in heterogeneous and fractured media

open access: yesOil & Gas Science and Technology, 2020
Numerical modeling of two-phase flows in heterogeneous and fractured media is of great interest in petroleum reservoir engineering. The classical model for two-phase flows in porous media is not completely thermodynamically consistent since the energy ...
Gao Huicai   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Blindness and science conceptualization

open access: yesETD: Educação Temática Digital, 2019
This paper presents the results of a research with the objective of understanding how the process of science conceptualizing occurs from the perspective of congenitally blind students and teachers or specialists in visual impairment.
Estéfano Vizconde Veraszto   +3 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Landform Monitoring and Warning Framework Based on Time Series Modeling of Topographic Databases

open access: yesGeosciences, 2015
Global Positioning System (GPS) and geodetic control networks are used today for analyzing and monitoring time-dependent crustal deformations, providing a series of accurate positional measurements to deliver information on positional changes and ...
Sagi Dalyot
doaj   +1 more source

Thermal cooling performance of convective non-Newtonian nanofluid flowing with variant power-index across moving extending surface

open access: yesScientific Reports, 2022
This communication focuses on assessing the effectiveness of nanoparticles, and a power-law variation fluid on a moving stretching surface is analyzed. Newtonian fluids for different nanomaterials are considered due to its industrial demand.
M. Ferdows   +3 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Home - About - Disclaimer - Privacy