High‐Concentration Antibody Formulation via Solvent‐Based Dehydration
Amorphous solid antibodies are encapsulated into hydrogel microparticles through a solvent‐based dehydration process. The solvent extracts water from antibody solution droplets, causing the antibody to concentrate, and precipitation of the antibody into amorphous solid is induced.
Talia Zheng +3 more
wiley +1 more source
Photothermal nanodiamonds with quantum sensing capabilities generate lysosome‐confined hyperthermia, enabling simultaneous temperature and radical detection via diamond sensing. This localized thermal and oxidative stress drives pro‐inflammatory (M1) macrophage polarization, revealing a new strategy for precision immunomodulation through subcellular ...
Kaiqi Wu +11 more
wiley +1 more source
Macrophages Mediate Mesoscale Brain Mechanical Homeostasis
We investigated the role of infiltrating immune cells in sculpting the developing brain. Using Brillouin microscopy and active microrheology, we found microglia actively maintain tissue viscoelasticity. Moreover, colony stimulating factor one receptor (CSF1R)‐driven stromal remodeling alters brain mechanics in vivo. These findings link immune activity,
Woong Young So +11 more
wiley +1 more source
Fatigue and quality of sleep jointly influence the association between physical activity and health-related quality of life in patients with chronic kidney disease: a cross-sectional study. [PDF]
De Gucht V +3 more
europepmc +1 more source
Liquid Metal Microrobots for Magnetically Guided Transvascular Navigation
Liquid metal‐based microrobots combine magnetic steering, intrinsic X‐ray visibility and softness, to navigate blood vessels even against flow. Under clinically relevant magnetic fields, liquid metal microrobots roll along vessel walls, cross endothelial barriers, and accumulate in target tissues.
Xiaohui Ju +7 more
wiley +1 more source
From physical modalities to energy-responsive biomaterials: Current strategies and challenges in tendon-to-bone healing. [PDF]
Zhang L +13 more
europepmc +1 more source
Physical Therapy Modalities and Alternative Methods in Treatment of Soft Tissue Lesions [PDF]
openaire +1 more source
Materials and System Design for Self‐Decision Bioelectronic Systems
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng +9 more
wiley +1 more source
Advances in Non-Pharmacological Strategies for DOMS: A Scoping and Critical Review of Recent Evidence. [PDF]
Di Lorenzo L +6 more
europepmc +1 more source
This study reports the first implantable resin cement capable of orientation‐sensitive Magnetic Particle Imaging (MPI). By coating the cement with an ultrathin iron film, the authors achieve a strong, angle‐dependent MPI signal that enables non‐ionizing, real‐time tracking of both implant position and orientation, opening new possibilities for safe ...
Gabriel C. Pinto +10 more
wiley +1 more source

