Results 201 to 210 of about 152,996 (259)

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Comparative efficacy and acceptability of treatment options for depressive disorders in children and adolescents: protocol of a network meta-analysis. [PDF]

BMJ Open
Guo J, Lu Z, Zhang Y, Sun Y, Kang Z, Sun J, Zhao G, Feng X, Yuan R, Zhu Y, Yu T, Yang Y, Chen H, Yue W.   +13 more
europepmc   +1 more source

Effectiveness of telerehabilitation versus home exercise and in-person therapy for nonoperatively managed tendinopathy: A systematic review and meta-analysis. [PDF]

J Int Med Res
Fan S, Noor S, Arunkumar Y, Bi Z, Guo Y, Zhang L.   +5 more
europepmc   +1 more source

Comparative effectiveness of different core muscle training regimens for chronic non-specific low back pain: a systematic review and meta-analysis. [PDF]

Front Med (Lausanne)
Liu Y, Yu Y, Lu F, Liu J.
europepmc   +1 more source

An in vitro comparison of cold atmospheric plasma and methylene blue-mediated antimicrobial photodynamic therapy with 660 nm laser on Streptococcus mutans biofilms. [PDF]

Lasers Med Sci
Arastouei MA, Azizi A, Vahedi M, Pourhajibagher M.   +3 more
europepmc   +1 more source

Trajectories of processing speed in multiple sclerosis across disease-modifying therapies. [PDF]

J Neurol
Guo J, Johansson E, Hillert J, Olsson T, Alfredsson L, Hedström AK.   +5 more
europepmc   +1 more source

Is helmet therapy effective in positional plagiocephaly? A systematic review and proposal for an updated management algorithm. [PDF]

Childs Nerv Syst
Castaño-Bustos D, Agudelo-Arrieta M, Ocampo-Navia MI, Chacón-Valencia SE, Pérez-Méndez W, Vergara-Lago M.   +5 more
europepmc   +1 more source