Results 211 to 220 of about 85,149 (286)

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander   +5 more
wiley   +1 more source

‘Paper care not patient care’: Nurse and patient experiences of comprehensive risk assessment and care plan documentation in hospital

open access: yesJournal of Clinical Nursing, Volume 32, Issue 3-4, Page 523-538, February 2023., 2023
Abstract Aims and Objectives To explore organisation‐wide experiences of person‐centred care and risk assessment practices using existing healthcare organisation documentation. Background There is increasing emphasis on multidimensional risk assessments during hospital admission. However, little is known about how nurses use multidimensional assessment
Catherine Paterson   +2 more
wiley   +1 more source

(2R,6R)‐hydroxynorketamine prevents opioid abstinence‐related negative affect and stress‐induced reinstatement in mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Opioid use disorder (OUD) is a pressing public health concern marked by frequent relapse during periods of abstinence, perpetuated by negative affective states. Classical antidepressants or the currently prescribed opioid pharmacotherapies have limited efficacy to reverse the negative affect or prevent relapse ...
Andria Michael   +7 more
wiley   +1 more source

Medical Aid in Dying: Europe’s Urgent Medico-Ethical Challenge

open access: yesInternational Journal of Public Health, 2023
Uwe Güth   +5 more
doaj   +1 more source

Safety and effectiveness of fingolimod in Japanese patients with multiple sclerosis: Results of a post‐marketing surveillance study

open access: yesClinical and Experimental Neuroimmunology, EarlyView.
Abstract Objective Fingolimod is the first oral sphingosine‐1‐phosphate receptor modulator approved in Japan for multiple sclerosis (MS). A large Japanese observational study of fingolimod in patients with MS was carried out to support its safety and effectiveness in a real‐world setting.
Noriko Sato   +7 more
wiley   +1 more source

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