Results 51 to 60 of about 2,565,699 (299)

Physics of the Mind [PDF]

open access: yesFrontiers in Systems Neuroscience, 2016
Is it possible to turn psychology into "hard science"? Physics of the mind follows the fundamental methodology of physics in all areas where physics have been developed. What is common among Newtonian mechanics, statistical physics, quantum physics, thermodynamics, theory of relativity, astrophysics… and a theory of superstrings?
openaire   +3 more sources

Information and Physics [PDF]

open access: yesInformation, 2012
In this paper I discuss the question: what comes first, physics or information? The two have had a long-standing, symbiotic relationship for almost a hundred years out of which we have learnt a great deal. Information theory has enriched our interpretations of quantum physics, and, at the same time, offered us deep insights into general relativity ...
Vedral, V, Vedral, V
openaire   +2 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Teaching quantum interpretations : revisiting the goals and practices of introductory quantum physics courses [PDF]

open access: yes, 2015
This work was supported in part by NSF CAREER Grant No. 0448176, NSF DUE No. 1322734, NSF IUSE No. 1432204, the University of Colorado, and the University of St Andrews.Most introductory quantum physics instructors would agree that transitioning students
Charles Baily   +3 more
core   +1 more source

PHYSICALLY IMPOSSIBLE?

open access: yesEDULEARN Proceedings, 2019
Halfway between the experiment and the focus group, between the quiz and a game, we have experienced a new format to \"focus\" on sustainability and the fundamental laws of thermodynamics and its principles. Concepts as reversibility, efficiency and entropy, are then \"visualized\" by the participants, showing the relations with the economic value ...
Domenici, D., Mazzitelli, G.
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

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