Results 31 to 40 of about 4,276,673 (241)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim +7 morewiley +1 more sourceDesign and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş +5 morewiley +1 more sourceReconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...Lukas Drexler, Markus R. Busch, Reinhard Sterner +2 morewiley +1 more sourceReport and recommendations on multimedia materials for teaching and learning quantum physics [PDF]
, 2015 An international collaboration of physicists, affiliated with Multimedia Physics for Teaching and Learning (MPTL) and MERLOT, performed a survey and review of multimedia-based learning materials for quantum physics and quantum mechanics.Mason, B, Silva, J, Santi, L, Kohnle, A, Melder, T, Girwidz, R, Dębowska, E, Arpornthip, T, Greczyło, T, Michelini, M +9 morecore +1 more sourceMicrobiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille +3 morewiley +1 more sourceStructure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.Alex J. Vecchiowiley +1 more sourcePeripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini +8 morewiley +1 more sourceFlavor physics in the quark sector [PDF]
, 2008 In the past decade, one of the major challenges of particle physics has been to gain an in-depth understanding of the role of quark flavor. In this time frame, measurements and the theoretical interpretation of their results have advanced tremendously. A Smith, Christopher, Isidori, G, C. Tarantino, F. Martinez Vidal, Tonelli, D, Becher T, J. Laiho, Flynn, J. M., R. V. Kowalewski, Maltman, K, G. Eigen, Smith, C., F. Harr, R., Gambino P., R Faccini (16065512), Passemar, Emilie, Powell A., Asner, David Mark, Cabibbo N., Jüttner, A, P. Krokovny, Goto, Toru, Sozzi, M., Harr, RF, Scholz EE, Schwartz, Alan Jay, Bona M., Kronfeld AS, M. Palutan, Coleman J. P., Libby, J, Antonelli M, Rotondo M, L. Silvestrini, Schneider, O., Martinez-Vidal, F., Bozzi, C., Schwartz, AJ, Libby J., Gershon T. J., Smith C., buras, A., N. Cabibbo, T. Goto, Dalseno, JP, Sacco, Roberto, Soni A, Bloise, C., C.H. Davies, Dungel W., S. van de Water, R., Simula, S., Westhoff S., petrov, A., Paradisi, Paride, A. J. Schwartz, Masiero A., Westhoff, Susanne, Dingfelder, J., P. Koppenburg, J. Marciano, W., A.V. Telnov, V. Telnov, A., Lopes Pegn, D, harr, R., Antonelli, M, Antonelli, Mario, T. E. Latham, Towner I. S., D. P. Cronin Hennessy, Bevan, A, Tantalo N., Flynn, J.M., Lunghi E, Rotondo, M, M. Moulson, kowalewski, R., T.J. Gershon, Prell, Soeren Andre, Gambino, P, Isidori G., Prell, S., Coleman, J. P., Feldmann, T., Towner, Ian S., Lubicz, V., Buras, A.J., Schumm BA, Coleman, J.P., Bozzi, C, Cabibbo, N, A.H. Hoang, Mohanty, G., Brod, J., Tantalo, N, Libby, J., Carbone A, M. Wingate, Tonelli D., Masiero, A., Di Lodovico, Francesca, R. F. Harr, Brod, J, Parsa Z., Becher, Thomas, Sozzi M, I.K. Furic, Martin, E. C., Towner, I. S., Buras, AJ, Hoang, André, Dalseno, J. P, J. Libby, Brod J., Lüth, VG, Gambino, Paolo, latham, T., Tonelli D, jaffe, D., R.S. Van De Water, Stocchi, A., Hoang, AH, Bondar, Alexander E., Spradlin P., Grojean, Christophe, Spradlin P, Lu, C. D, Di Lodovico F., M. Rotondo, Lueth V. G., Pecjak, B.D., Gershon, TJ, Mescia F., DiLodovico, F, Simonetto, F., Kronfeld, A.S., Plaster, B, Jager, Sebastian, Sciascia, B, Lu, C.D, Schumm, B.A, Dingfelder J., A. Sibidanov, P. Urquijo, A.J. Bevan, Harr, R.F, Doležal, Z., Rescigno, M, Bevan A. J., V. Cirigliano, Marciano, W.J, Sonnenschein, Lars, Simonetto, Franco, A. J. Buras, Dingfelder, J, Lunghi, Enrico, K. Furic, I., Donati, S., Patel, M., Wingate M., SOZZI, MARCO STANISLAO, Tantalo, N., C. Schwanda, O. Schneider, Dalseno, J.P, Giagu S, V. G. Luth, Golowich, E., Xie, Y, hoang, A., H. Hoang, A., Rotondo M., E. Jaffe, D., Mohanty, G. B., Scholz, E. E, Koppenburg, P, J. Zupan, Soni, A., Trabelsi, K, Petrov A. A., Shipsey IJ, Koppenburg, Patrick Stefan, Trabelsi K., Martinez-Vidal F, F. Ferroni, Parsa, Zohreh, flynn, J., Schneider O, Khodjamirian, A., J. Rademaker, Moulson, M., Brod, Joachim, Harr, R. F, Scholz, EE, Golowich, Eugene, Hoang A. H., Van de Water, RS, Haisch, U.A., Coleman, JP, Palutan M, Bona, M, Nishid. S, Masiero A, Faccini, R., I.S. Towner, H. Neufeld, Lubicz, Vittorio, Bozzi, Concezio, Buras, A, Jaffe, D.E, Kronfeld, A. S., S. Westhoff, Schumm, Bruce Andrew, Lu, C. D., Schilling, C.J, A. Powell, Ricciardi, Stefania, Kowalewski, R.V, G. Mohanty, Zupan, J., Bevan AJ, Telnov, AV, Spadaro, T, Antonelli, M., Sonnenschein L., Asner, DM, luth, V., Bloise C., J.P. Coleman, Shipsey, IJ, Kowalewski, RV, Egede, U., Fernando Ferroni, Y. Xie, Shipsey, I.J, Isidori G, Franco, Enrico, E. Scholz, E., Sonnenschein, L, Van de Water, R.S., Grojean C., Sciascia, Barbara, J. van Kooten, R., Bona, M., Flynn, JM, Di Lodovico F, Tarantino, Cecilia, Rescigno M., Zupan J, Maltman K., D. E. Jaffe, Volpi, Guido, Towner, IS, Wingate, M, Mohanty G, Gardi E, E. E. Scholz, Bondar, A., Martin, Emilie Claire Mutsumi, Harr, Robert Francis, Shigemitsu, J, Gershon, T.J., Scholz, E.E, Kooten, RJV, Cronin-Hennessy DP, N.i.s.h.i.d. S, Schilling, C. J, Lunghi, E, Powell, A., Plaster B., G. Isidori, Eigen G, Egede U., Offen, N, Franco, E., F. Martinez-Vidal, H. Davies, C., Schneider, O, Feldmann, T, E. Golowich, Pich, A., Martin, E. C, Plaster, Brad, Bauer, Daniel Adams, Moulson M, M. Patel, E. Latham, T., S. Jager, Martinez Vidal F, S. Nishida, Schwartz, A.J., Latham TE, V.G. Luth, G. Lanfranchi, Virto, J., Schwanda, C., Sacco, R., Pegna, DL, Pierini M, Flynn, J. M, Nishida, S., Jaffe D. E., Eigen, G, Neufeld H, Petrov, AA, Martinelli G, Van Kooten, Richard J., Palutan, M., Hurth, Tobias, Shigemitsu J., Petrov, A.A., G. Lüth, V., Offen N., Di Lodovico, F, Juettner, A., Davies CH, Koppenburg P, Prell S, Guadagnoli D., Rotondo, Marcello, Neufeld H., Nishida, Shohei, M. Pierini, Robbe P., Latham, T. E., R.J. Van Kooten, Khodjamirian A, M. Flynn, J., Van Kooten, R.J., Sciasci, B, Wilkinson G, Lopes Pegna, D., Gambino, P., Lüth, V.G, A. Pich, Moulson M., Haisch, UA, Simula, S, C. D. Lu, Spadaro T., Flynn J. M., Petrov, A.A, Laiho J., Latham T. E., C. Grojean, Dungel W, Dalseno J. P., A. A. Petrov, Golowich, E, Parsa, Z, Laiho, J, Furic, I. K., T. Hurth, Schumm, B. A, Telnov, Alexandre V., Donati S, Spradlin, Patrick Michael, Cavoto, Gianluca, U.A. Haisch, Sibidanov, A., Spadaro, T., Jaffe, D.E., Franco E, Lunghi E., Telnov, A.V., Bevan, A.J., Bon, M, Nishida S, Cronin-Hennessy, D.P, Moulson, M, Soni, A, Serrano, Justine, Hoang AH, Eigen G., Xie Y., Greub C, Juttner, Andreas, Hurth, T., Feldmann T., R. Wanke, Hoang, A. H, S. Simula, Cabibbo, N., Kronfeld, A. S, Haisch, U.A, Pich Zardoya, Antonio, Martin EC, Rademaker J, Schumm, BA, J. P. Dalseno, Urquijo P, Paradisi, P., Kronfeld, Andreas Samuel, Bloise C, Furic IK, Schilling CJ, Luth, V. G., Greub, C., Dingfelder J, Kowalewski, R. V, Lu, Cai-Dian, T. Becher, Schneider, Olivier, Towner, I.S, Marciano, WJ, Z. Parsa, Bevan, AJ, Antonelli M., Offen, N., Spradlin, P., Smith, C, Powell, A, Juttner, A., Pegna D. Lopes, bevan, A., J.M. Flynn, Pegna DL, Coleman JP, Harr, R. F., M. Asner, D., Wingate, M., Prell S., Bona, Marcella, D. M. Asner, Sordini, Viola, D. Lopes Pegna, Furić, I.K, Simonetto, F, Wilkinson, G., Donati, Simone, U. A. Haisch, Robbe, P., J. Shipsey, I., Franco, E, P. Paradisi, K. Trabelsi, Shigemitsu J, Lueth VG, E. Passemar, S. Prell, Goto T, R. Faccini, Furić, IK, Mohanty, Gagan Bihari, Tarantino, C., Towner IS, Davies C. H., E.E. Scholz, Grojean, C., Xie Y, Lopes Pegna, D, Guadagnoli D, Rescigno M, Haisch, U. A., Blanke, M, Martinez-Vidal, F, Furic I. K., Bozzi C., Latham, T. E, Schneider O., Libby J, Buras, A. J., davies, C., Schwanda C, Tantalo, Nazario, W.J. Marciano, Franco E., Isidori, Gino, Pars, Z, Petrov AA, Isidori, G., Cronin Hennessy DP, Pich A., J. M. Flynn, G. Cavoto, Tarantino, C, Krokovny P, Marciano, W. J., Blanke M., Giagu, Stefano, J. P. Coleman, Latham, TE, M. Fujikawa, D. Lu, C., Jaeger, S., Marciano, William J., J. Gershon, T., Simul, S, Stocchi A., S. Kronfeld, A., Paradisi P, Cronin-Hennessy, D.P., I. S. Towner, Van Kooten, RJ, D. Guadagnoli, Wanke, R., Passemar, E, Cirigliano, V, Gardi, E, B. Sciascia, Lanfranchi, G., Cronin-Hennessy, D. P., V. Lubicz, E. Franco, Juettner, A, C. J. Schilling, Bondar A, S. Ricciardi, Water, RSVD, Dalseno, J. P., Rodrigues E, Faccini, Riccardo, C.J. Schilling, Pierini, M, A. Carbone, Rademaker, J., G. Wilkinson, Serrano J, Krokovny P., kronfeld, A., Giagu, S, Stocchi, Achille, Neubert M., Hoang, A.H., R.F. Harr, Urquijo, Phillip, Paradisi, P, Prell, S, Virto, Javier, I. K. Furi¢, Blanke, M., Gambino P, Maltman K, Spadaro, Tommaso, V. Mateu, Davies, C.H, Rescigno, Marco, Telnov AV, Sacco R., Hurth T., Simula, Silvano, D. Bauer, Kowalewski, R. V., Neubert, M, Kronfeld A. S., scholz, E., Guido Martinelli, J. Shigemitsu, Golowich E, Schilling C. J., F. Mescia, Neubert, Matthias, Scholz, E. 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S., Ciuchini M., Haisch UA, Soni A., Jaeger S, Sonnenschein L, Sozzi, M, Koppenburg, P., Bona M, Patel, M, Smith C, Martinelli G., Gardi, E., pecjak, B., Flynn, Jonathan M., Ricciardi S., Scholz, E.E., Harr, R.F., Harr R. F., Petrov, A. A., Hoang, A. H., Ferroni F, Guadagnoli, D, Sibidanov A., Wilkinson G., Soni, Amarjit, Van Kooten, R. J., E. C. Martin, Tarantino C, Zupan, Jure, Rademaker, J, Becher T., Tonelli, D., Sciascia B., Patel M, Robbe, Patrick, A. J. Bevan, Rademaker J., van de water, R., Martinez Vidal, F, Martínez-Vidal, Fernando, Wingate M, I. J. Shipsey, Mohanty, G, Bauer D., Brod J, Mescia F, Juettner A, Beneke M., C. Bozzi, A.J. Buras, Donati, S, T.E. Latham, Jaffe, D. E., Bondar A., R.V. Kowalewski, Trabelsi, Karim, Mohanty G., E. Rodrigues, Cronin-Hennessy, Daniel P., Cavoto, G., A. Bondar, V. Sordini, Pierini, M., Stocchi A, Jäger, S, Latham, T.E, Lüth, V. G, J. Serrano, Coleman, J.P, B. D. Pecjak, Van Kooten, R.J, Harr RF, Lu CD, Dalseno, J.P., Shipsey, I.J., Flynn JM, Bloise, C, Ricciardi, S., Robbe P, Marciano, William Joseph, telnov, A., Petrov, A. A, Martin, E.C., Beneke, M, R. S. Van De Water, Asner, D. M., Schwartz AJ, Dungel, W., Lanfranchi G., C. H. Davies, Jager S, Offen N, Buras AJ, Juttner A, J. Bevan, A., U. Egede, Pecjak, B.D, Mescia, F, A. Khodjamirian, Khodjamirian A., Offen, Nils, Faccini R., G. Martinelli, A. V. Telnov, Volpi, G., Becher, Thomas G., J. Schwartz, A., A. Stocchi, Lueth, VG, Pich A, V. Kowalewski, R., B.A. Schumm, Davies, C. H., Kowalewski, Robert V., Palutan M., Tantalo N, M. Sozzi, Greub C., Silvestrini, Luca, Van de Water, R. S., Lueth, V. G., Cavoto G, CARBONE, ANGELO, Cirigliano V., Schwanda C., Shipsey, Ian P.J., Gershon, Timothy John, Beneke, Martin, Schumm, B.A., Marciano W. J., W. J. Marciano, A. Limosani, Grojean, C, I.J. Shipsey, Sonnenschein, L., Cirigliano, V., Limosani A., Carbone, A, Mescia, F., Spradlin, P, Sebastian Jaeger (4462564), Hurth T, Haisch U. A., Lunghi, E., Fujikaw, M, Martin E. C., Koppenburg P., Lanfranchi, G, Martinelli, Guido, towner, I., Shipsey I. J., Davies, CH, M. Neubert, Wingate, Matthew Bowen, Serrano, J., Wanke, R, Telnov A. V., Petrov, Alexey A., Juettner A., Van Kooten R. J., Sibidanov, A.L., N. Tantalo, Scholz, Enno E., Plaster B, lu, C., P. Spradlin, Latham, T.E., Sacco R, Schumm B. A., Urquijo P., E. Lunghi, Bevan, A. J., Giagu S., Giagu, S., Goto, T, Xie, Y., Cronin Hennessy, D. P, Stocchi, A, Laiho, J., Becher, T, Paradisi P., B. Plaster, Beneke M, Asner, D.M, Di Lodovico, F., Westhoff S, haisch, U., J. Virto, Powell A, Passemar E., Martinez Vidal F., cronin-hennessy, D., D. Pecjak, B., J. Dingfelder, Mescia, Federico, Masiero, A, Schwartz, A.J, Scholz E. E., Towner, I. S, Asner D. M., C. Smith, Schilling, Christopher James, Jaffe, DE, Bauer, D., Virto J, Volpi G., Mateu V., Cavoto G., Krokovny, P., T. J. Gershon, Schwartz, A. J, Parsa, Z., Rodrigues, E, Ciuchini, Marco, Carbone, A., Mateu V, Westhoff, S, Guadagnoli, Diego, Carbone A., Gardi, E.; id_orcid, Faccini R, A.J. Schwartz, Rodrigues E., Fujikawa M, Ciuchini M, Spadaro T, Furic, Ivan K., Beneke, M., Hoang, Andre H., Urquijo, P, M. Blanke, Hoang, A.H, B. A. Schumm, Van Kooten, R. J, Eigen, G., Ricciardi S, Trabelsi K +999 morecore +1 more source
