Results 71 to 80 of about 1,622,011 (325)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Lecture notes in Medical and Biological Physics [PDF]

open access: yes, 2015
Matter most commonly exists as a solid, liquid, or gas; these states are known as the three common phases of matter. Solids have a de nite shape and a speci c volume, liquids have a de nite volume but their shape changes depending on the container in
Yunda, Andrii Mykolaiovych   +2 more
core  

General U(N) gauge transformations in the realm of covariant Hamiltonian field theory

open access: yes, 2013
A consistent, local coordinate formulation of covariant Hamiltonian field theory is presented. While the covariant canonical field equations are equivalent to the Euler-Lagrange field equations, the covariant canonical transformation theory offers more ...
H Weyl   +3 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Complex-Dynamical Extension of the Fractal Paradigm and Its Applications in Life Sciences [PDF]

open access: yes, 2004
Complex-dynamical fractal is a hierarchy of permanently, chaotically changing versions of system structure, obtained as the unreduced, causally probabilistic general solution of arbitrary interaction problem (physics/0305119, physics/9806002).
Kirilyuk, Andrei
core  

Dynamics of Nonequilibrium Deposition with Diffusional Relaxation

open access: yes, 1995
Models of adhesion of extended particles on linear and planar substrates are of interest in interpreting surface deposition in colloid, polymer, and certain biological systems. An introduction is presented to recent theoretical advances in modeling these
Privman, Vladimir
core   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

Space station needs, attributes and architectural options study. Volume 1: Executive summary [PDF]

open access: yes
Planetary explorations, Earth observations, space physics, astronomy-astrophysics, solar physics, life/biological/medical sciences, materials processing in space, communications, and technology development are addressed.

core   +1 more source

Beyond the fuzzy lock-and-key: spontaneous symmetry shifts and glycan/lectin logic gates [PDF]

open access: yes, 2012
Changes in the molecular topology of glycan/lectin interaction may explain observed reaction punctuation driven by experimental gradients in reactant concentration. Adoption of a 'biological renormalization' perspective from statistical physics
Rodrick Wallace
core   +1 more source

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