Results 71 to 80 of about 1,669,840 (313)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Physical structures. Forming physical fields and manifolds. (Properties of skew-symmetric differential forms) [PDF]

open access: yesarXiv, 2004
It is shown that physical fields are formed by physical structures, which in their properties are differential-geometrical structures. These results have been obtained due to using the mathematical apparatus of skew-symmetric differential forms. This apparatus discloses the controlling role of the conservation laws in evolutionary processes, which ...
arxiv  

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Quantum gloves: Physics and Information [PDF]

open access: yesarXiv, 2004
The slogan information is physical has been so successful that it led to some excess. Classical and quantum information can be thought of independently of any physical implementation. Pure information tasks can be realized using such abstract c- and qu-bits, but physical tasks require appropriate physical realizations of c- or qu-bits.
arxiv  

Amplitude Death: The emergence of stationarity in coupled nonlinear systems

open access: yes, 2012
When nonlinear dynamical systems are coupled, depending on the intrinsic dynamics and the manner in which the coupling is organized, a host of novel phenomena can arise.
Prasad, Awadhesh   +2 more
core   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel   +3 more
wiley   +1 more source

B Physics (Experiment) [PDF]

open access: yesarXiv, 2010
In past few years the flavor physics made important transition from the work on confirmation the standard model of particle physics to the phase of search for effects of a new physics beyond standard model. In this paper we review current state of the physics of b-hadrons with emphasis on results with a sensitivity to new physics.
arxiv  

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

open access: yesFEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji   +3 more
wiley   +1 more source

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

open access: yesFEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Can classical physics agree with quantum physics on quantum phenomena? [PDF]

open access: yesarXiv, 2015
Classical physics fails where quantum physics prevails. This common understanding applies to quantum phenomena that are acknowledged to be beyond the reach of classical physics. Here, we make an attempt at weakening this solid belief that classical physics is unfit to explain the quantum world.
arxiv  

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