Results 31 to 40 of about 116,831 (260)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Particles, Objects, and Physics [PDF]
, 2005 This thesis analyses the ontological nature of quantum particles. In it I argue that quantum particles, despite their indistinguishability, are objects in much the same way as classical particles. This similarity provides an important point of continuity
Justin C. Pniower +2 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Development and uses of upper-division conceptual assessments
, 2015 The use of validated conceptual assessments alongside conventional course exams to measure student learning in introductory courses has become standard practice in many physics departments.
Chasteen, Stephanie V. +13 more
core +1 more source
Physics of attosecond pulses produced via high harmonic generation [PDF]
, 2009 The physics of extreme ultraviolet attosecond pulse trains generated during the interaction between an intense laser pulse and a gas medium is presented, including a simple model based on the solution of the classical equations of motion of an electron ...
Mauritsson, Johan +12 more
core +1 more source
, 2021 Kip Thorne and Roger Blandford’s monumental Modern Classical Physics is now available in five stand-alone volumes that make ideal textbooks for individual graduate or advanced undergraduate courses on statistical physics; optics; elasticity and fluid ...
Thorne, Kip S, Blandford, Roger D
core +3 more sources
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Probability and Typicality in Deterministic Physics [PDF]
, 2010 Recently it has been argued that typicality considerations play a crucial explanatory role in deterministic theories in physics (e.g. classical statistical mechanics and Bohmian mechanics).
Hemmo, Meir, Shenker, Orly R.
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