Results 31 to 40 of about 48,679 (259)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Methodological Fundamentalism: or why Batterman’s Different Notions of ‘Fundamentalism’ may not make a Difference [PDF]
, 2006 I argue that the distinctions Robert Batterman (2004) presents between ‘epistemically fundamental’ versus ‘ontologically fundamental’ theoretical approaches can be subsumed by methodologically fundamental procedures.
William M Kallfelz, Kallfelz, William
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Fluid Convection, Constraint and Causation [PDF]
, 2011 Complexity–nonlinear dynamics for my purposes in this essay–is rich with metaphysical and epistemological implications but is only recently receiving sustained philosophical analysis.
Bishop, Robert
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FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
, 2015 This book presents a focused, readable account of the principal physical and mathematical ideas at the heart of fluid dynamics. Graduate students in engineering, applied math, and physics who are taking their first graduate course in fluids will find ...
Bernard, Peter S
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Downward Causation in Fluid Convection [PDF]
, 2006 Recent developments in nonlinear dynamics have found wide application in many areas of science from physics to neuroscience. Nonlinear phenomena such as feedback loops, inter-level relations, wholes constraining and modifying the behavior of their parts,
Robert C. Bishop, Bishop, Robert C
core +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
A highly adaptive three dimensional hybrid vortex method for inviscid flows and helically symmetric vortex equilibria [PDF]
, 2012 This thesis is concerned with three-dimensional vortex dynamics, in particular the modelling of vortex structures in an inviscid context. We are motivated by the open problem of regularity of the inviscid equations, i.e.
Lucas, Daniel
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