Results 61 to 70 of about 692,439 (328)

Valid Physical Processes from Numerical Discontinuities in Computational Fluid Dynamics [PDF]

International Journal of Hypersonics, 2010
Due to the limited cell resolution in the representation of flow variables, a piecewise continuous initial reconstruction with discontinuous jump at a cell interface is usually used in modern computational fluid dynamics methods. Starting from the discontinuity, a Riemann problem in the Godunov method is solved for the flux evaluation across the cell ...
Xu, Kun, Sun, Quanhua, Yu, Pubing
openaire   +4 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Atomistic Hydrodynamics and the Dynamical Hydrophobic Effect in Porous Graphene

, 2016
Mirroring their role in electrical and optical physics, two-dimensional crystals are emerging as novel platforms for fluid separations and water desalination, which are hydrodynamic processes that occur in nanoscale environments. For numerical simulation
Eaves, Joel D., Strong, Steven E.
core   +2 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Patterns on liquid surfaces: cnoidal waves, compactons and scaling

, 2000
Localized patterns and nonlinear oscillation formation on the bounded free surface of an ideal incompressible liquid are analytically investigated . Cnoidal modes, solitons and compactons, as traveling non-axially symmetric shapes are discused.
A. Ludu, Abraham, Apfel, J.P. Draayer, Kevrekidis, Lamb, Lu, Ludu, Ludu, Ludu, Ludu, Ludu, Ludu, Ludu, Marston, Natarajan, Natarajan, Novikov, Rebbi, Rosenau, Shi, Shi, Tian, Trinh, Trinh, Trinh, Tsamopoulos, Ustinov   +27 more
core   +1 more source

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source

The Borexino Thermal Monitoring & Management System and simulations of the fluid-dynamics of the Borexino detector under asymmetrical, changing boundary conditions

, 2017
A comprehensive monitoring system for the thermal environment inside the Borexino neutrino detector was developed and installed in order to reduce uncertainties in determining temperatures throughout the detector.
A. Goretti, A. Ianni, Benziger, Colombo, D. Bravo-Berguño, F. Calaprice, F. Gabriele, F. Inzoli, Garg, Gariazzo, Kuehn, M. Carlini, Malalasekera, Maneschg, P. Cavalcante, R. Mereu, R.B. Vogelaar, T. Wright, Vinyoles, Yin, Z. Yokley   +20 more
core   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

Fluids in cosmology

, 2013
We review the role of fluids in cosmology by first introducing them in General Relativity and then by applying them to a FRW Universe's model. We describe how relativistic and non-relativistic components evolve in the background dynamics.
A Albrecht, A Aviles, A Carnero, A Friedmann, A Friedmann, AA Penzias, AD Dolgov, AD Dolgov, AD Dolgov, AD Linde, AG Cohen, AG Riess, AG Riess, AG Walker, AH Guth, B Hoyle, BA Reid, BD Sherwin, BF Schutz, C Marinoni, CM Chambers, CP Ma, CP Ma, CW Misner, DH Lyth, DJ Eisenstein, DJ Eisenstein, DJ Eisenstein, DJ Fixsen, EJ Copeland, EP Hubble, EV Linder, EW Kolb, FL Bezrukov, G Gamow, G Gamow, G Mangano, G Steigman, GF Smoot, GFR Ellis, GW Gibbons, HB Richer, HJ Seo, HP Robertson, HP Robertson, HP Robertson, J Carlson, J De-Santiago, J Kim, J Magaña, JC Mather, JL Cervantes-Cota, JL Cervantes-Cota, JL Cervantes-Cota, JL Cervantes-Cota, JR Bond, JV Narlikar, L Amendola, L Anderson, L Kofman, L Kofman, LF Abbott, M Chevallier, M Trodden, M Zaldarriaga, MS Turner, N Jarosik, N Turok, P Bernardis, PJ Steinhardt, R Allahverdi, R Amanullah, R Jimenez, RH Cyburt, RR Caldwell, RR Caldwell, S Carrol, S Davidson, S Perlmutter, S Weinberg, S Weinberg, S Weinberg, SW Allen, T Giannantonio, T Matos, U Seljak, VF Mukhanov, W Hu, Y Aoki   +88 more
core   +1 more source