Results 31 to 40 of about 732,442 (243)

Commissioning of the J-PET detector for studies of decays of positronium atoms [PDF]

, 2017
The Jagiellonian Positron Emission Tomograph (J-PET) is a detector for medical imaging of the whole human body as well as for physics studies involving detection of electron-positron annihilation into photons.
Białas, P., Curceanu, C., Czerwiński, E., Dulski, K., Gajos, A., Gorgol, M., Głowacz, B., Hiesmayr, B. C., Jasińska, B., Kisielewska, D., Korcyl, G., Kowalski, P., Kozik, T., Krawczyk, N., Krzemień, W., Kubicz, E., Mohammed, M., Moskal, P., Niedźwiecki, Sz., Pawlik-Niedźwiecka, M., Pałka, M., Raczyński, L., Rudy, Z., Sharma, N. G., Sharma, S., Shopa, R. Y., Silarski, M., Skurzok, M., Wieczorek, A., Wiślicki, W., Zgardzińska, B., Zieliński, M.   +31 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Re-engineering a nanodosimetry Monte Carlo code into Geant4: software design and first results

, 2009
A set of physics models for nanodosimetry simulation is being re-engineered for use in Geant4-based simulations. This extension of Geant4 capabilities is part of a larger scale R&D project for multi-scale simulation involving adaptable, co-working ...
Gargioni, E., Grichine, V., Pia, M. G.
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Search for a Possible Spontaneous Emission of Muons from Heavy Nuclei

, 2010
A search for an exotic natural radioactivity of lead nuclei, using nuclear emulsion sheets as detector, is described. We discuss the experimental set-up of a test performed at the Gran Sasso National Laboratory (Italy), the event simulation, data ...
Giorgini, M.
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Deterministic Partial Differential Equation Model for Dose Calculation in Electron Radiotherapy

, 2009
Treatment with high energy ionizing radiation is one of the main methods in modern cancer therapy that is in clinical use. During the last decades, two main approaches to dose calculation were used, Monte Carlo simulations and semi-empirical models based
B Dubroca, Börgers C, Coulombel J-F, Davison B, Dubroca B, Dubroca B, Gifford K A, Hensel H, Krieger T, Lehmann C, M Frank, Mihalas D, Modest M F, Mott N F, Müller I, R Duclous, Salvat F, Tervo J, Vassiliev O N, Zerby C D   +19 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The GEANT4 Object Oriented Simulation Tookit [PDF]

, 1999
Geant4 is a toolkit for the simulation of the passage of particles through matter, developed with advanced software engineering techniques. Its application areas include high energy and nuclear physics experiments, space physics, $9 medical physics and ...
Pia, M G
core