Results 31 to 40 of about 376,502 (249)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano +2 morewiley +1 more sourceSomatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan +6 morewiley +1 more sourceExtracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic +9 morewiley +1 more sourceSearch for anomalous production of prompt like-sign lepton pairs at root s=7 TeV with the ATLAS detector [PDF]
, 2012 ATLAS Contributor: Paul Douglas Jackson of School of Chemistry and Physics, University of Adelaide, Adelaide, Australia Extent: 41p.An inclusive search for anomalous production of two prompt, isolated leptons with the same electric charge is presented ...G. Khoriauli, Alessandria, F, S. O. Holmgren, Arce ATH, Smizanska, M, Blair, R, Keung, J, Ask S., Strang, M, G. Eigen, Aguilar-Saavedra, J. A., Carminati, L., C. Le Maner, Cantero, J., Hubaut, F., M. Mazur, E. Etzion, P. Hansson, Skottowe, H, Borissov, G., F. Dinut, Hellman, S, Harper, D, Oliver García, Elena, Y. Smirnov, Higón Rodríguez, Emilio, D. Chakraborty, Bona M., Cavalli Sforza, M, Kanzaki, J, C. Booth, Bloch I., J. M. Seixas, Rodd, N, A. Talyshev, T. Naumann, Pranko, A, Clark A., Jakoubek, T, Fernando, W, Ahlen, S. P., J. Keung, G. Nunes Hanninger, Brooijmans G., Leney, K, J. Tojo, Daya-Ishmukhametova, R, Butler J. M., M. Villa, Abreu, H, Huettmann, A, A. Tonoyan, W. J. Dearnaley, B. Caron, Bundock A. C., Acharya B. S., Siragusa, G, S. Kaneti, Vacek, V, Carlino, G., Oliveira, M, Bogaerts, J, I. Gough Eschrich, Snyder, S, Kirk, J, Ziolkowski, M, P. Grenier, V. Dao, Lefebvre, M, T. Mueller, M. Uslenghi, Bernat, P., G. Alexandre, I. N. Aleksandrov, Engl, A, A. Juste Rozas, Asai S, Arnault, C., Bortolotto, V, Kiryunin, A, M. Klein, Moreno Llácer, María, Valkar, S, D. M. Rebuzzi, T. Todorov, Caminada L. M., T. Sumida, Knue, A, M. Medinnis, L. Mijović, Harris, O, D. Turecek, Cheatham, S, Joram, C, Mashimo, T, M. H. Genest, P. Stavina, Kersten, S, M. S. Weber, Reale, V, Vassilakopoulos, V, Bruneliere, R, S. Menke, Darlea, G, M. Agustoni, Massol, N, Benoit M, L. Rumyantsev, Canelli F., Kawamoto, T, K. Tackmann, Castaneda Miranda, E, Manfredini, A, J. E. García Navarro, Michal, S, R. Camacho Toro, D. G. Charlton, Salihagic, D, B. Budick, J. Zhu, Bronner, J., J. B. Liu, J. Toth, González de la Hoz, Santiago, Cornelissen, T, J. L. Pinfold, Barr, A, J. Griffiths, Nisati, A, Moursli E, Strong, J, M. F. Tripiana, Deviveiros, P, M. Werner, Marx, M, V. B?scher, A. F. Saavedra, A. Ludwig, Burckhart H., V. Vrba, P. T. Keener, Selbach, K, V. Andrei, M. Wright, A. Petridis, Orr, R, Carrillo Montoya GD, O. Le Dortz, G. Cataldi, Bini, C, Hedberg, V, D. A. Milstead, Kobel, M, E. Pasqualucci, Bednyakov, V, Lubatti, H, A. Polini, CAMARRI, PAOLO, Puzo, P, Nozka, L, Yu, J, R. Veness, Lancon, E, Marroquim, F, Yu, D, Z. Zhang, Abdelalim, A. A., Liss, T, Ellis, N, Benslama, K., Ellis, K, Norberg, S, Baak, M, Muino, P, Allwood Spiers, S. E., K. Iordanidou, Oreglia, M, Parzefall, U, F. M. Newcomer, Hillier, S, T. Nattermann, Huseynov, N, Bellina, F, N. Benekos, Charlton, D. G., R. Bates, Sadrozinski, H, Arnault C., Pauly, T, V. Kral, F. Niedercorn, R. Ueno, Kaci, M, R. Ströhmer, Krumshteyn, Z, T. Kuhl, G. Romeo, Smirnova, O, Arguin, J-F., B. Vachon, Smirnova, L, S. Schmitt, Diehl, E, Oberlack, H, L. Serkin, Avolio, G, Beau T., Broggi F., M. Garcia-Sciveres, Castillo Gimenez, V., T. M. Liss, Nikolic-Audit, I, Weng, Z, Sw. Banerjee, M. C. N. Fiolhais, Milov, A, A. J. Lowe, R. Seuster, Haller, J, P. Loch, E. Piccaro, Buat, Q., S. Monzani, Donadelli, M, Ciocca, C., G. Bobbink, R. Bartoldus, Bhimji W, Epp, B, Rybar, M, H. M. Gray, Cantrill, R, Kroha, H, Clark PJ, Meroni, C, Tayalati, Y, Ciftci AK, Branchini P, Y. Bai, Lie, K, Kawamura, G, Cardarelli R., E. Sarkisyan-Grinbaum, S. Bentvelsen, B. Martin dit Latour, Davies, M, Byszewski, M, Andeen T, Klemetti, M, Davies, E, Blumenschein U, Camacho Toro, Reina Coromoto, Buchholz P., Fournier, D., G. Otero y Garzon, Y. Makida, C. Bertella, M. G. Wilson, Dudarev, A, Busato E, L. Batkova, W. Bell, Bittner, B., A. Dudarev, E. Ertel, Lange, C, Chafaq, A., Lantzsch, K, Grivaz, J.-F., Battistin M, I. Bloch, Bromberg C., P. Wienemann, R. Armadans, Beddall, A, Tsiskaridze, V, Alhroob, M., Tsiskaridze, S, S. Heisterkamp, Kurata, M, Ren, Z, Salek, D, P. Calfayan, G. Anders, Aliev M., J. M. Izen, Fisher, M, CHIEFARI, GIOVANNI, H. G. Sander, Bartoldus, R., Bagnaia P, Lagouri, T, J. Ebke, Odaka, S, D. C. O’Neil, Walsh, B, D. S. Popovic, Barajas, C, S. Cole, de Jong, P., H. Ji, E. Vilucchi, J. Lorenz, P. Vankov, A. Gibson, Baranov, S, J. R. Carter, Mechnich, J., Baranov S. P., Soukharev, A, S. Vallecorsa, Ciftci, R., M. T. Pérez García-Estañ, M. Raymond, X. S. Anduaga, C. Stanescu, Hajduk, Z, S. Mahmoud, Alexandre, G, Aleksandrov IN, Burgess, T., Kado, M., M. Pohl, M. Ciubancan, Brendlinger, K, Bocchetta, S, F. Hahn, Klok, P, J. Kroseberg, J. Labbe, H. Li, Chen Y., P. J. Clark, Aharrouche, M, G. Alexander, H. Ma, Bremer, J., Cowan, G, Gadfort, T, AbouZeid, O, Chromek Burckhart, D., Shupe, M, Chen X., Cakir O., P. Cirkovic, Calafiura P., Beloborodova O, Cattai, A., Biesiada J., Hryn'ova, T, Brandt G., M. Schumacher, P. Federic, Carrillo-Montoya, G. D., J. Meyer, Makovec, N, Lundberg, B, L. A. Bella, J. Buchanan, Lundberg, J, Bruschi, M, S. Allwood Spiers, Lundberg, O, Giorgi, F, Sauvage, G, Bednyakov, V. A., Frank, T, de la Torre, H., Azuelos, G, Cerutti, F, Schwegler, P, Cheplakov A., G. L. Darlea, R. Hauser, Bouhova-Thacker EV, Vladoiu, D, Calvet, D., Blocker C., L. Fayard, H. Schulz, Nanava, G, G. Poulard, N. Amram, V. B. Vinogradov, Hassani, S, M. Morii, Cavalleri P., Hillert, S, Cavasinni V., Wingerter-Seez, I., Krieger, N, P. Gerlach, Krieger, P, Boumediene D., D. Kar, B. Liberti, Childers, J, B. H. Smart, García García, Carmen, G. Lenzen, F. Derue, M-A. Dufour, Brandt A., Chu, M. L., T. Djobava, Belotskiy K., P. W. Phillips, H. G. Wilkens, Simic, L, Bachacou H., Brelier B, Anduaga XS, C. Schiavi, Subramania, H, T. Nunnemann, A. Salamon, B. M. M., S. Stern, K. Bos, Mechtel, M, Ancu L. S., Kono, T, Cerrito L., Bunse M., M. Caprini, J. Rothberg, Buttinger, W., T. Wenaus, Paramonov, A, Joffe, D, Farrell, S, P. K. Behera, Gray, H, Gray, J, F. Quinonez, Rosenbaum, G, Blocker C, Gillberg, D, B. K. Gjelsten, D. M. Gingrich, Banas, E., Bianchi, R. M., Esposito, B, J. Schaarschmidt, Beau T, Bacci, C, T. Nobe, T. Colombo, B. Guo, D. Rahm, Tani, K, V. Martinez Outschoorn, Ciocca, C, H. van der Graaf, Bell W. H., T. Kobayashi, Brandt O., Catastini, P, O. Simard, Mechnich, J, Prokoshin, F, C. P. Paleari, De Groot, N, Weigell, P, P. Behera, M. Aurousseau, Ciftci R., Burckhart, H., H. K. Hadavand, A. Lucotte, Plamondon, M, X. Wu, B. Alvarez Gonzalez, Royon, C, J. Ferencei, Vartapetian, A, H. Okawa, R. Keeler, Basye A., S. B. Harpaz, Cantrill, R., A. M. Castaneda Hernandez, Abdallah J, P. Dervan, S. Chekulaev, Hare, G, Blazek, T., Koutsman, A, P. Koevesarki, D. Levin, P. Schacht, J. Arguin, Knecht, N, Caloba, L, Kogan, L, Clarke, R. N., Tassi, E, Bertin A, Calderini G, Simoniello, R, C. Friedrich, H. Burckhart, S. Panitkin, Tikhomirov, V, P. U. E. Onyisi, Garrido, M, B. Osculati, Vuillermet, R, M. S. Neubauer, Oda, S, M. Baker, Cowden, C, Brock I., S. Kabana, Del Peso, J, F. Conventi, Le Dortz, O, Y. Coadou, Kass, R, J. Ginzburg, R. Ciftci, Protopopescu, S, A. Chitan, C. Haber, R. Alon, D. Giugni, P. Vokac, Z. Zhao, Chen S., Antos, J, Rubinskiy, I, Kaczmarska, A, W. Brooks, Gorfine, G, Z. Zhan, Alexa, C, Anulli F, S. Crépé-Renaudin, G. Negri, Bogaerts, J. A., Bugge L., N. Davidson, H. Yang, Bhimji W., Morettini, P, Nadal, J, Garrido M. D. M. C., Bucci, F, T. J. Neep, P. Gutierrez, Harpaz, S, P. Laycock, K. Sliwa, R. D. St. Denis, Stroynowski, R, Romeo, G, A. M. C., J-Y. Hostachy, Torregrosa, E, D'Auria, S, M. Shiyakova, Ko, B, Yurkewicz, A, Teixeira-Dias, P, G. Alimonti, J. M. Butler, Chelstowska, M.A., Chen H., Sicho, P, M-L. Andrieux, Z. Czyczula, Bella, L. Aperio, Esch, H, Y. Tayalati, Chiefari, G, Capriotti D, K. Kroeninger, Christidi I. A., Papadelis, A, S. M. Consonni, J. Jia, Stanitzki, M, Karakostas, K, do Vale, M, S.w. Banerjee, Ciapetti G, von der Schmitt, H, Boonekamp M, Addy TN, ALOISIO, ALBERTO, M. S. Alam, P. F. Giraud, E. Coniavitis, Anghinolfi F, Chu M. L., Aguilar Saavedra, J, C. Lapoire, Lungwitz, M, Lenz, T., Khalek, S, Petschull, D, C. P. Buszello, Huegging, F, Renstrom, P. A. Bruckman, Shimojima, M, Bozovic Jelisavcic I, Barreiro F, R. Mandrysch, M. Lassnig, Reisinger, I, C. Petridou, P. Staroba, Paleari, C, Abramowicz, H., Ilic, N, Raas, M., Yasu, Y, A. Olariu, Meng, Z, S. Kalinin, Cristinziani, M, A. Dafinca, Blondel, A., Le Guirriec, E., Caron, S., Caputo R., Luijckx, G., Del Papa, C, Smolek, K, K. Nagai, S. Tanaka, Barlow N, A. E. Barton, Y. S. Gao, Peso Malagón, José del, E. Devetak, M. Ridel, Armbruster, A. J., Badescu, E, K. Ellis, J. A. Wilson, Albert, J., K. Mönig, Chapman, J, Chekanov S., Arik, M, Castaneda-Miranda, E, S. Pashapour, Washbrook, A, Matricon, P., C. Malone, D. R. Quarrie, O. Bulekov, A. Coccaro, D. Dobos, Miguens, J, Borissov G., Arik, E, G. Piacquadio, D. Berge, F. Prokoshin, E. Panagiotopoulou, S. Hamilton, A. Manabe, Belloni A., Nurse, E, N. Morange, Vorwerk, V, Damazio, D, S. Goldfarb, Brau, B., V. Pozdnyakov, P. Savard, Chekulaev, S, S. Yanush, T. Rador, P. Steinberg, Curatolo, M, Dervan, P, J. Stark, M. A. B. do Vale, Krejci, F, P. S. Miyagawa, B. Gorini, Cavaliere V, G. Iacobucci, Canale, V, O'Neale, S, Bierwagen, K., Gazis, E, A. A. Solodkov, Stoicea, G, Lj. Simic, Shimizu, S, Eschrich, I, Ciftci R, A. G. Olchevski, Chakraborty, D, Bolnet, N, C. Clémens, J., Wiglesworth, C, C. Luci, Sbrizzi, A, Rezvani, R, Bellagamba L, Chromek Burckhart, D, Azuma, Y, J. P. Thomas, I. Boyko, R. Febbraro, Chiodini, G, Casado, M. P., Etzion, E, M. Kaci, Stanescu-Bellu, M, J. Farley, L. P. Caloba, Chavda V, Chilingarov A, Chavda V., Caughron S, Binet S, D. R. Tovey, Gorini, E, Gorini, B, Antonov, A., M. Kado, V. Vorwerk, R. M. Fakhrutdinov, S. L. Wu, Aefsky, S., Klier, A, Jez, P, J. Ernst, E. Mountricha, N. Grau, Chromek-Burckhart, D, Takeda, H, Fassi, Farida, Burckhart H, Igonkina, O., Brunet, S, B. Kaplan, H. M. Braun, Takahashi, Y, Allport PP, E. Eisenhandler, Loebinger, F, Bundock, A. C., Sansoni, A, D. Lellouch, H. Boterenbrood, Virchaux, M, Dearnaley, W, Belanger-Champagne C, O. Sasaki, Menke, S, Tua, A, Vlasak, M, Fabbri, L, Oram, C, Tsiakiris, M., van Huysduynen, L, R. Nicolaidou, N. Zhou, Benchekroun, D, Johansson, K, Bangert A., Johansson, P, F. Djama, M. Lichtnecker, K. Copic, T. M. Hong, G. Vegni, P. S. Mangeard, M. Simonyan, Chen C., Hadley, D, A. Gemmell, J. C. Vermeulen, Bawa, H, Hubaut, F, M. Mineev, Wall, R, Fassi, F, Gagliardi, G, Massa, I, M. P. Goulette, Degenhardt, J, G. Polesello, U. Schnoor, Caughron, S., S. F. Brazzale, G. Spigo, Axen, D, Biscarat, C, R. Herrberg, C. T. Potter, Clemens JC, A. C. König, Dell'Acqua, A, K. M. Smith, P. Ge, Aleksandrov I. N., Poblaguev, A, Barajas C. A. C., J. A. Dassoulas, Kaneti, S, Kroseberg, J, T. Koffas, Schmidt, E, V. Tsiskaridze, Bahinipati, S, Blanchard, J. B., J. Bouchami, U. Schäfer, Jia, J, Swedish, S, B. A. Gonzalez, Y. Kataoka, G. Baccaglioni, H. Lacker, Perini, L, Koetsveld, F, Dabrowski, W, R. Van Berg, H. J. Lubatti, W. Kozanecki, E. I. Rosenberg, M. W. Wolter, Batley, J, Korcyl, K, J. Jakubek, Bromberg, C., Majewski, S, Bansil H. S., Vinogradov, V, Anghinolfi, F., M. Pecsy, Azuma Y, Orlov, I, Policicchio, A, Prokofiev, K, E. Meoni, Andeen, T., S. A. Olivares Pino, Hays, C, Ciapetti, G, B. Walsh, Bilokon H., Becks KH, Abi, B., K. Stoerig, Baines JT, Mc Donald, J, D. A. A. Geerts, N. van Eldik, E. Richter-Was, Aleksa M, T. Schwindt, B. Stelzer, A. Tykhonov, K. Kordas, A. Mayne, Richter-Was, E, B. Galhardo, Adye, T, E. Gornicki, H. Khandanyan, Berry, T., E.-E. Kluge, Di Simone, A, Nordberg, M, Pinto, B, Y. Zhou, Beccherle, R, Kuutmann EB, Satsounkevitch, I, Ahmad A, A. Becker, Arutinov, D., K. Korcyl, D. Lissauer, T. Del Prete, E. Le Guirriec, Brock R., Alessandria, F., Berry T, M. Rybar, Buda, S, J. T. Childers, N. Castro, Petridou, C, Vlachos, S, V. Chernyatin, Wijeratne, P, Tollefson, K, Calkins R, V. Solovyev, H. Braun, J. D. Chapman, M. Bosman, B. G. Pope, Becker S., M. J. Woudstra, Podlyski, F, M. Romano, Alimonti G, Berghaus, F., Jeanty, L, Veloso, F, Barklow, T., L. Aperio Bella, Boyko I. R., Fortin, D, W. Cleland, Pope, B, Stugu, B, Massaro, G, T. Akdogan, Caloi R, W. Verkerke, Caron, B, Soldevila, U., Andrei, V, Consonni, S, N. Besson, P. Cavalleri, Ragusa, F, Bloch I, M. Düren, E. Carquin, G. Mornacchi, Ukegawa, F, Karnevskiy, M, Nechaeva, P, Mirabelli, G, Caron, S, Tokushuku, K, Bee, C, V. Vercesi, Amelung, C, Volpi, M, Hostachy, J, G. Volpini, A. Sanchez, Volpi, G, S. Grinstein, Caso, C, O'Brien, B, Cirilli M., Hanawa, K, Camarri P., Simmons, B, E. Arik, T. Nakamura, A. Ferretto Parodi, Renaud, A, S. Bieniek, F. Canelli, Caminada LM, Ancu LS, Short, D, Catinaccio A, Sumida, T, Ask, S., Santoni, C, F. Marzano, Evans, H, Harvey, A, Cavasinni V, Hong, T, Lacava, F, Hong, V, G. Kawamura, T. Haruyama, Hanke, P, S. Xie, Zenz, S, S. Fazio, U. K. Yang, Cameron, D, S. Demers, Walker, R, M. P. Sanders, Kataoka, M., Wilhelm, I, Solodkov, A, R. Rezvani, T. Hayakawa, Kozanecki, W, Schultz-Coulon, H, Chikovani, L., Miñano Moya, Mercedes, J. Jovicevic, Shmeleva, A, Hayden, D, F. Winklmeier, Åsman, B., Campana, S +999 morecore +1 more sourceAutomated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller +6 morewiley +1 more sourceHyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi +9 morewiley +1 more sourcePhysics and causation [PDF]
, 2009 The paper makes a case for there being causation in the form of causal properties or causal structures in the domain of fundamental physics. That case is built in the first place on an interpretation of quantum theory in terms of state reductions so that Michael Esfeld, Esfeld, Michaelcore +1 more sourceMARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando +8 morewiley +1 more sourceWhat Else (Besides the Syllabus) Should Students Learn in Introductory Physics? [PDF]
, 2009 We have surveyed what various groups of instructors and students think students should learn in introductory physics. We started with a Delphi Study based on interviews with experts, then developed orthogonal responses to “what should we teach non ...Brian R. Belland, Mel Sabella, Barrantes, Analia, Charles Henderson, Pritchard, David E., Analia Barrantes, David E. Pritchard, Belland, Brian R., Chandralekha Singh +8 morecore +1 more sourceA nationwide student survey on biochemistry learning resources in Italy
FEBS Open Bio, EarlyView.We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).Anna Marabotti, Ivano Eberini, Maria Luisa Genova, Francesca Mensitieri, Francesco Malatesta +4 morewiley +1 more source