Results 21 to 30 of about 2,175,580 (244)

Quantifying the unknown: issues in simulation validation and their experimental impact

, 2011
The assessment of the reliability of Monte Carlo simulations is discussed, with emphasis on uncertainty quantification and the related impact on experimental results. Methods and techniques to account for epistemic uncertainties, i.e.
Batic, M., Begalli, M., Han, M., Hauf, S., Hoff, G., Kim, C. H, Kuster, M., Pia, M. G., Quintieri, L., Saracco, P., Seo, H., Weidenspointner, G., Zoglauer, A.   +12 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Virtualizing physical space

, 2021
Die eigentlichen Kosten für Virtual Reality Anwendungen entstehen nicht primär durch die erforderliche Hardware, sondern durch die Nutzung von physischem Raum, da die eins-zu-eins Abbildung von physischem auf virtuellem Raum die immersivste Art von Navigation ermöglicht.
openaire   +2 more sources

Gauge Symmetry in Phase Space, Consequences for Physics and Spacetime

, 2010
Position and momentum enter at the same level of importance in the formulation of classical or quantum mechanics. This is reflected in the invariance of Poisson brackets or quantum commutators under canonical transformations, which I regard as a global ...
Bars, Itzhak
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Search for Cold Dark Matter and Solar Neutrinos with GENIUS and GENIUS-TF

, 2002
The new project GENIUS will cover a wide range of the parameter space of predictions of SUSY for neutralinos as cold dark matter. Further it has the potential to be a real-time detector for low-energy (pp and 7Be) solar neutrinos.
H. V. Klapdor-Kleingrothaus, H. V. Klapdor-Kleingrothaus, H. V. Klapdor-Kleingrothaus, H. V. Klapdor-Kleingrothaus, H. V. Klapdor-Kleingrothaus, H. V. Klapdor-Kleingrothaus, H. V. Klapdor-Kleingrothaus, H. V. Klapdor-Kleingrothaus, H. V. Klapdor-Kleingrothaus, H. V. Klapdor-Kleingrothaus, H. V. Klapdor-Kleingrothaus, H. V. Klapdor-Kleingrothaus, H. V. Klapdor-Kleingrothaus, Heidelberg-Moscow Collab., I. V. Krivosheina, J. Ellis, J. Hellmig, J. N. Bahcall, J. N. Bahcall, L. Baudis, L. Baudis   +20 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Unitary Quantum Physics with Time-Space Noncommutativity

, 2004
In this work quantum physics in noncommutative spacetime is developed. It is based on the work of Doplicher et al. which allows for time-space noncommutativity. The Moyal plane is treated in detail.
, , A. Kempf, A. P Balachandran, A.P. Balachandran, A.P. Balachandran, B. Bistrovic, C Molina, F. Lizzi, However see in this connection D.S. Bak, J. Madore, L. Susskind, N.N. Bogoliubov, P Teotonio-Sobrinho, R. Brunetti, R. Haag, R.F. Streater, S. Doplicher, S. Doplicher, T. R Govindarajan   +19 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Finite Approximations to Quantum Physics: Quantum Points and their Bundles

, 1993
There exists a physically well motivated method for approximating manifolds by certain topological spaces with a finite or a countable set of points.
A.P. Balachandran, Aleksandrov, Aneziris, Avron, Balachandran, Balachandran, Bamonte, Bombelli, Creutz, de Gennes, Drouffe, E. Ercolessi, G. Bimonte, Hilton, Hooft, Ivashchenko, Jaffe, Kleinert, Kogut, McCoy, Munkres, P. Teotonio-Sobrinho, Parisi, Rabin, Sorkin, Sorkin, Stanley, Van Dyck   +27 more
core   +1 more source