Results 271 to 280 of about 1,880,647 (379)

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Species-Specific Responses of Kiwifruit Seed Germination to Climate Change Using Classifier Modeling. [PDF]

Plants (Basel)
Hsieh TY, Li F, Huang SL, Chien CT.
europepmc   +1 more source

From Sample to Mixed Reality: A Translational 3D MALDI Imaging Platform for Advanced 3D Spatial Omics Analysis of 3D Cell Culture Disease Models

Advanced Science, EarlyView.
A comprehensive technology platform enables high‐fidelity, volumetric MALDI imaging of 3D cell cultures by integrating custom embedding molds, a semi‐automated computational framework for 3D reconstruction, voxel‐instead of pixel‐based biomarker discovery, and immersive mixed reality data exploration.
Stefania Alexandra Iakab, Jonas Cordes, Thomas Enzlein, Florian Keller, Kevin Kastner, Theresa Mulholland, Björn Christian Fröhlich, Lars Gruber, James Lucas Cairns, Stefan Schmidt, Mathias Hafner, Richard Schneider, Johannes Betge, Frank Fischer, Julian Reichwald, Rüdiger Rudolf, Carsten Hopf   +16 more
wiley   +1 more source

Cancer Cell Dormancy and Chemotherapy Resistance. [PDF]

J Cancer
Hu J, Zhou W, Zhao Y, Li P, Zhao Z, Wang W, Wang W, Wang Y.   +7 more
europepmc   +1 more source

UNDERSTANDING THE PHYSIOLOGICAL AND MOLECULAR BASIS OF SEED DEVELOPMENT, GERMINATION AND DORMANCY

PUSARLA, SUSMITHA, CHAKRABORTY, ANINDA, ROUT, SANGHAMITRA   +2 more
openalex   +1 more source

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

Advanced Science, EarlyView.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello, Sandra Hauser, Michael Seifert, Christopher K. Barlow, Joel R. Steele, Emma Salisbury, Daniel Croagh, Kathryn S. Stok, Anna V. Taubenberger, Ralf B. Schittenhelm, Daniela Loessner   +10 more
wiley   +1 more source

Microenvironmental and Molecular Pathways Driving Dormancy Escape in Bone Metastases. [PDF]

Int J Mol Sci
Bakir M, Dabaliz A, Dawalibi A, Mohammad KS.   +3 more
europepmc   +1 more source

NIR Ratiometric Fluorescent Antibody‐Drug Conjugate for Metastatic Ovarian Cancer Theranostics and Treatment Response Monitoring

Advanced Science, EarlyView.
In vivo optical imaging enhances antibody‐drug conjugate (ADC) optimization by enabling real‐time monitoring of stimulus‐responsive drug behavior. We report n501‐CYMMAF, a ratiometric theranostic with strong target affinity and low‐dose efficacy for ovarian metastasis.
Cheng Li, Zezhong Yu, Tao Pu, Yanling Wu, Gang Wang, Youhua Xie, Tianlei Ying, Zhenlin Yang, Yibing Shi   +8 more
wiley   +1 more source

Seed coat-derived ABA regulates seed dormancy of <i>Pyrus betulaefolia</i> by modulating ABA and GA balance. [PDF]

Front Plant Sci
Wang X, He L, Li J, Bai S, Teng Y, Hui W.   +5 more
europepmc   +1 more source

Physiology of peach (Prunus persica (L) Batsch) meristems under tropical conditions. Effect of shoot orientation, defoliation and chemical treatments to modify their dormancy

, 1982
Gorka Sancho
openalex   +1 more source