Comparative Analysis of the Central Nervous System Safety Pharmacology Profiles of Caffeine and Taurine in Male and Female Mice Using a Modified Irwin Test. [PDF]
Cho SH +5 more
europepmc +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Hippocampal and neocortical dynamics at physiological or febrile temperature are not modified in the pre-epileptic period in a mouse model of Dravet ...
Lavigne J, Curia G, Mantegazza M
core
Thermoregulation in hot-dry and warm-humid heat stress during cycling among males. [PDF]
Zhao X, McDermott BP, Butts CL.
europepmc +1 more source
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen +15 more
wiley +1 more source
Hollow-degree-tuned Prussian blue-mesoporous silica nanoplatforms for chemo-photothermal cancer therapy with preliminary microfluidic perfusion evaluation. [PDF]
Xi J +9 more
europepmc +1 more source
A Generative Neuro‐Symbolic AI for Protein Sequence Design
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne +12 more
wiley +1 more source
Non optimal temperatures and chronic cardiovascular diseases. [PDF]
Münzel T +7 more
europepmc +1 more source
A Monolithic Janus Hydrogel Pressure Sensor for Wearable Motion and Physiological Monitoring
This work reports a monolithic Janus hydrogel pressure sensor featuring integrated conductive PEDOT and insulating PEGDA layers. The fabricated device achieves a rapid response time, a wide operating range, and good cyclic durability. The sensor demonstrates robust performance in tracking dynamic human joint motions, offering a scalable strategy for ...
Syed Atif Ali +7 more
wiley +1 more source

