Results 221 to 230 of about 3,654,033 (309)

The Governance Gap: Democratizing Drug Development Through Decision Architecture

Clinical Pharmacology &Therapeutics, EarlyView.
Drug development is most exposed to governance failure where it can least afford it, in global health. The field has more predictive power than at any point in its history and roughly the same failure rate it had a decade ago. We argue that this paradox persists because the field has invested heavily in prediction science while neglecting decision ...
Craig R. Rayner, Nancy E. Martin, Danielle Smith, Eliza Kruger, Carl M.J. Kirkpatrick, Goonaseelan (Colin) Pillai, Katy Moore, Darrell Nix, Cristina Donini, Jakob P. Cramer, Edmundo Muniz, Natalia Muniz, Ernst Bos, Douglas McNair, Shyam Bhaskaran, Mark Sullivan, Dan Hartman   +16 more
wiley   +1 more source

Hitting the Wall in Marathon Running: An Integrative Psychophysiological and Durability-Based Review. [PDF]

J Funct Morphol Kinesiol
Grivas GV, Alkasasbeh WJ, Amawi AT.
europepmc   +1 more source

Does Internal Corporate Social Responsibility Drive Employee Well‐Being? Evidence From a Positive Balance Perspective

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The significance of fostering an internal corporate social responsibility (ICSR) plan to advance employee well‐being is not fully understood. This article explores employee well‐being from a positive balance perspective, combining the strategic approach to Internal Corporate Social Responsibility with the Theory of subjective well‐being ...
Teresa C. Herrador‐Alcaide, João Correia Leitão, Montserrat Hernández‐Solís, Dina Pereira   +3 more
wiley   +1 more source

Pacing Profiles in Half-Marathon and Marathon Running Based on Performance Level, Sex, and Age: A Narrative Review. [PDF]

Medicina (Kaunas)
Ristanović L, Stojiljković S, Ćuk I, Weiss K, Rosemann T, Knechtle B.   +5 more
europepmc   +1 more source

Establishment of pediatric reference ranges for circulating naïve and memory T and B cell subsets guided by the human immunophenotyping consortium standardization initiative: A large, single center U.S. experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley   +1 more source

Antidepressant Misuse in Esports: A Review of Pharmacology, Adverse Effects, Pharmacokinetics and Biomatrix‐Based Detection for Anti‐Doping Applications

Drug Testing and Analysis, EarlyView.
This review highlights the misuse of antidepressants as potential cognitive‐enhancing agents in Esports. Despite pharmacological effects that overlap with those of psychostimulants, antidepressants remain an under‐recognised source of doping in Esports.
Kassim Ali Salum, Shao‐Hsin Hung, Meng‐Tsang Hsieh, Mei‐Chich Hsu, William Chih‐Wei Chang   +4 more
wiley   +1 more source

Left Bundle Branch Area Pacing: Innovation Requires Vigilance. [PDF]

JACC Case Rep
König S, Bode K.
europepmc   +1 more source

Parasitoid insects unveil complex patterns of functional change across elevational bands

Ecography, EarlyView.
Climate change is rapidly reshaping how insects interact with their environment, potentially disrupting ecosystem complexity and essential functioning. While functional homogenisation has been extensively investigated for charismatic insect taxa, particularly pollinators, the response of parasitoids remains largely overlooked.
Michela Gabrieli, Lara Marcolin, Luca Santini, Pierfilippo Cerretti, Moreno Di Marco   +4 more
wiley   +1 more source

Lignocellulosic Triboelectric Materials for Energy Harvesting and Emerging Applications: A Review on Lignin‐Molecular Engineering toward Improved Performance

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Contrasting sustainable biomass with depleting petroleum resources, this review charts the evolutionary timeline of lignin‐based TENGs. We systematically evaluate their fundamental mechanisms, enhancement strategies, and applications in green self‐powered electronics.
Yuxin Yang, Boyu Du, Yuwen Wang, Tian Tang, Yuxuan Xie, Jiajun Zhang, Yajun Zhang, Jingyu Xu, Xing Wang, Chuanyin Xiong   +9 more
wiley   +1 more source

Optic Nerve Head Measurements Across Optical Coherence Tomography Platforms and Incidental Optic Nerve Head Drusen in Community Screenings

Eye &ENT Research, EarlyView.
ABSTRACT Background Automated vertical cup‐to‐disc ratio (VCDR) measurements are commonly used in optic nerve assessment, but measurements may vary across optical coherence tomography (OCT) platforms, particularly in eyes with atypical optic nerve anatomy such as optic nerve head drusen (ONHD).
Sedra T. Alabed, Aretha Zhu, Bernard C. Szirth, Albert S. Khouri   +3 more
wiley   +1 more source