Editorial: Insights into the molecular dynamics of stress physiology in allium crops. [PDF]
Front Plant SciDegani O, Khandagale K, Gawande S.
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Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
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MARU-MTL: A Mamba-Enhanced Multi-Task Learning Framework for Continuous Blood Pressure Estimation Using Radar Pulse Waves. [PDF]
Bioengineering (Basel)Xie J +5 more
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Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
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Leef: environmental neuroscience modeling for cognitive resilience. [PDF]
Front Hum NeurosciMorina E.
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Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
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"De Senectute" in the perioperative and critical care continuum-advancing personalized care for the geriatric patient at the intersection of frailty, aging, and multimorbidity. [PDF]
J Anesth Analg Crit CareD'Andria Ursoleo J, Bignami EG.
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Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
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Latest advances and controversies of exercise therapy in the management of type 2 diabetes. [PDF]
Front Endocrinol (Lausanne)Hao J, Zhang H.
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