Results 131 to 140 of about 7,637,456 (312)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Tripogon loliiformis elicits a rapid physiological and structural response to dehydration for desiccation tolerance

open access: yes, 2016
Resurrection plants can withstand extreme dehydration to an air-dry state and then recover upon receiving water. Tripogon loliiformis (F.Muell.) C.E.Hubb.
Williams, Brett   +3 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Immunohistochemical localization of Calcitonin Gene-Related Peptide and Substance P in the rat knee cartilage at birth

open access: yes, 2005
F. OLIVA MD, U. Tarantino MD, N. Maffulli MD, MS, PhD, FRCS(Orth) . "Immunohistochemical localization of Calcitonin Gene-Related Peptide and Substance P in the rat knee cartilage at birth" Physiological Research 2005;55(5):549 ...
OLIVA F   +4 more
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

OARS

open access: yes, 1979
Covers OCLC #1264104498 and OCLC #1274239742.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

The physiological and behavioural responses of sheep exposed to heat load within intensive sheep industries [PDF]

open access: yes, 2006
The live export and feedlotting industries are the major intensive sheep industries in Australia. During live shipment, sheep are exposed to prolonged periods of high heat and humidity, with little relief for several days, while environmental conditions ...
Stockman, Catherine Ann
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

An investigation into the use of infrared thermography as a tool to assess the physiological stress response in the horse [PDF]

open access: yes, 2011
The experiments reported in this thesis investigated the use of temperature measurement using infrared thermography (IRT) as an objective, non-invasive method to identify the physiological stress response in the horse.
Yarnell, K
core  

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