Results 151 to 160 of about 41,015 (217)

Iron overload disorders in adults: a comprehensive review of gonadal function, reproductive, and sexual health. [PDF]

Hum Reprod Update
Carlomagno F, Tenuta M, Sansone A, Rastrelli G, Sciarra F, Cangiano B, Isidori AM, Gianfrilli D, Krausz C.   +8 more
europepmc   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

From the G-spot to the H-zone (Haddad Zone): Exploring an Anatomical, Neurovascular, and Regenerative Framework for Female Sexual Function. [PDF]

Cureus
Haddad R.
europepmc   +1 more source

Granzyme B PET Imaging Reveals Lgmn+ Macrophage‐Mediated Immune Evasion and Guides Immunotherapy in EGFR‐TKI‐Resistant NSCLC

Advanced Science, EarlyView.
Graphical illustration of 68Ga‐GZB PET/CT imaging reveals immune dynamics post‐EGFR‐TKI resistance in NSCLC; Lgmn+ macrophages‐derived Lgmn‐containing extracellular vesicles inhibit glycolysis, induce CD8+ T cell exhaustion, and targeting Lgmn restores immunotherapy sensitivity.
Dongliang Wang, Wenqin Luo, Qiufang Liu, Wenxuan Tang, Bin Zhu, Jiwei Chen, Qian Zhou, Shuang Tang, Xiaoping Xu, Shaoli Song   +9 more
wiley   +1 more source

Identifying Sexuality and Intimacy Needs in Patients with Multiple Myeloma: A Cross-Sectional Survey.

Acta Haematol
Levy Yurkovski I, Peleg-Nesher S, Pazooky G, Zektser M, Votinov E, Frosinsky E, Vaxman I, Shoam V, Tadmor T, Kreiniz N.   +9 more
europepmc   +1 more source

From Prenatal Exposure to Adult Sexual Dysfunction: The Impact of Plastic-Derived Endocrine Disruptors on Testosterone Homeostasis and Erectile Function. [PDF]

Toxics
Stavros S, Christopoulos P, Kokkosi E, Moustakli E, Zikopoulos A, Potiris A, Daskalaki MA, Arkoulis I, Anagnostaki I, Vassilaki I, Kathopoulis N, Daskalakis G, Drakakis P.   +12 more
europepmc   +1 more source

Developmental Environmental Chronotoxicity by Polystyrene Nanoplastics Exacerbates High‐Fat Diet‐Induced Pediatric MAFLD Through Circadian Disruption and Mitochondrial Dysfunction

Advanced Science, EarlyView.
Polystyrene nanoplastics exacerbate high‐fat diet‐induced metabolic dysfunction in an age‐dependent manner. Juvenile mice exhibit greater susceptibility, characterized by circadian disruption, impaired mitochondrial function, reduced energy metabolism, and enhanced hepatic lipid accumulation.
Peihao Xu, Shuting Huang, Leilei Zhu, Junyi Huang, Kewei Li, Guangming Li, Jiannong Wu, Mingyuan Zhou, Fangmei Zhou, Zhishan Ding, Yingzhi Shen   +10 more
wiley   +1 more source

A Narrative Review of Psychological and Physical Rehabilitation in Infertility Treatment: Toward Holistic Outcomes Beyond Conception. [PDF]

Medicina (Kaunas)
Putra MADT, Endratamma MA, Akbar MF, A Hamid A, Mokhtar MH.   +4 more
europepmc   +1 more source

A Hepatocyte‐to‐Stellate Cell Axis Couples Alternate‐Day Fasting to Liver Fibrosis Resolution via ATG7 S‐Nitrosylation

Advanced Science, EarlyView.
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang, Mengqi Zeng, Cunxiao Sun, Yuhan Gou, Zhaode Feng, Weiqiang Lv, Chaoying Yan, Hansen Wu, Pengfei Zhang, Jie Xu, Ke Cao, Hao Li, Mingge Ding, Zhongbo Liu, Xing Zhang, Jiankang Liu, Xuan Zou, Zhihui Feng   +17 more
wiley   +1 more source

Sexual dysfunction in chronic hepatitis B: a comprehensive review of pathophysiology, clinical burden, and integrated management. [PDF]

Front Public Health
Muzammal S, Song CR, Peng JN, Wang YH, Chen EQ.   +4 more
europepmc   +1 more source