Results 51 to 60 of about 985,985 (267)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Physiological Stress in Laying Hens

Poultry Science, 2006
Stress responses in laying hens were mediated by continuous infusion of adrenocorticotropin (ACTH) via osmotic pumps. The ACTH was dissolved in saline solution (0.85%), and each pump delivered 8 IU of ACTH per kilogram of BW per day at the rate of 1 microL/h for 7 d. Control hens received pumps loaded with saline. Measurements were made at 6 d postpump
J Odihambo, Mumma, J P, Thaxton, Y, Vizzier-Thaxton, W L, Dodson   +3 more
openaire   +2 more sources

Comparison of Physiological Stress Indices in Anesthetized and Manually Restrained Leopard Sharks, Triakis semifasciata

Biology
Background: Leopard sharks (Triakis semifasciata) are abundant, coastal, eastern Pacific, mesopredatory sharks and are frequently managed in aquariums and zoos.
Meghan M. Holst, Catharine J. Wheaton, Alexandra N. Schoen, Jill V. Spangenberg, Kevin T. McEligot, Melissa L. Schouest, Charlene M. Burns, Natalie D. Mylniczenko   +7 more
doaj   +1 more source

Cardiac exercise imaging using a 3-tesla magnetic resonance-conditional pedal ergometer: Preliminary results in healthy volunteers and patients with known or suspected coronary artery disease

Cardiology Journal, 2023
BACKGROUND: Cardiac magnetic resonance imaging (CMR) remains underutilized as an exercise imaging modality, mostly because of the limited availability of MR-compatible exercise equipment.
Agnes Mayr, Gert Klug, Sebastian J. Reinstadler, Regina Esterhammer, Christian Kremser, Klemens Mairer, Bernhard Metzler, Michael F. Schocke   +7 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Dangers of the chronic stress response in the context of the microbiota-gut-immune-brain axis and mental health: a narrative review

Frontiers in Immunology
More than 20% of American adults live with a mental disorder, many of whom are treatment resistant or continue to experience symptoms. Other approaches are needed to improve mental health care, including prevention. The role of the microbiome has emerged
Alison Warren, Yvonne Nyavor, Aaron Beguelin, Leigh A. Frame   +3 more
doaj   +1 more source

O estresse do trabalhador de enfermagem: estudo em diferentes unidades de um hospital universitário [The stress of nursing workers: study in different units of a university hospital]

Revista Enfermagem UERJ, 2015
Este estudo objetivou discutir o nível de estresse oriundo do trabalho dos profissionais de enfermagem de três unidadesde um hospital universitário no Rio de Janeiro.
Celia Caldeira Fonseca Kestenberg, Ingryd Cunha Ventura Felipe, Felipe de Oliveira Rossone, Lívia Moreira Delphim, Michele Costa Teotonio   +4 more
doaj   +1 more source