Results 141 to 150 of about 2,132,125 (311)

Principal component analysis for physiological and biochemical traits in different rice genotypes.

open access: yes
Principal component analysis for physiological and biochemical traits in different rice genotypes.
Areeqa Shamshad (16847873)   +3 more
core   +1 more source

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang   +12 more
wiley   +1 more source

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

open access: yesAdvanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer   +17 more
wiley   +1 more source

Optimizing physiological performance, assimilate partitioning and productivity of late-sown wheat (Triticum aestivum L.) through mepiquat chloride application under nitrogen enrichment

open access: yesFrontiers in Agronomy
IntroductionLate sowing constrains grain yield formation in wheat by shortening the duration of post-anthesis assimilate accumulation and limiting the effective utilization of source-derived assimilates during grain filling. Optimizing nitrogen nutrition
Kavita Devi   +5 more
doaj   +1 more source

Mean statistical parameters estimated from RILs for eleven morpho-physiological traits under reproductive stage drought stress.

open access: yes, 2019
Mean statistical parameters estimated from RILs for eleven morpho-physiological traits under reproductive stage drought stress.
Sharat Kumar Pradhan (8138439)   +4 more
core   +1 more source

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

open access: yesAdvanced Science, EarlyView.
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao   +19 more
wiley   +1 more source

How do the Physiological and Spectral Behaviors of Eucalyptus Seedlings Respond to Different Water Restriction Conditions?

open access: yesForest Science and Technology
The use of remote sensing data from hyperspectral sensors offers advantages over other plant phenotyping methodologies. This technique enables non-destructive, largescale data acquisition, applicable not only in basic research but also in plant breeding.
Ricardo Gava   +8 more
doaj   +1 more source

Cancer‐Associated Fibroblasts Promote Glucose Metabolic Reprogramming and Progression of Triple‐Negative Breast Cancer via Exosomal circFAD104‐Mediated Intercellular Communication

open access: yesAdvanced Science, EarlyView.
CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang   +16 more
wiley   +1 more source

Genetic diversity studies for yield and physiological traits using principal component analysis in little millet

open access: yesElectronic Journal of Plant Breeding
Principal Component Analysis (PCA) was conducted to assess the genetic variability among 50 little millet genotypes based on yield and physiological traits.
T. Venkata Ratnam1 and L. Madhavi Latha2*
doaj   +1 more source

Quantitative Visualization of Intracellular Nanometabolism Using Peak‐Shifted Dual‐State Emissive FRET Nanoprobes

open access: yesAdvanced Science, EarlyView.
This study reveals the long‐elusive intracellular dissolution mechanism of carrier‐free nanomedicines. By utilizing peak‐shifted dual‐state emissive FRET nanoprobes (PDFNPs) that undergo a distinct ratiometric fluorescence peak shift upon disassembly, we achieve real‐time, quantitative tracking of dissolution kinetics in live cells.
Farsai Taemaitree   +18 more
wiley   +1 more source

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