Results 71 to 80 of about 2,132,125 (311)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Descriptive statistics for different morpho-physiological traits of 40 wheat genotypes included in the study.

, 2022
Descriptive statistics for different morpho-physiological traits of 40 wheat genotypes included in the study.
Imran Akhtar (12078109), Muhammad Imran Latif (12078106), Ali Tan Kee Zuan (9105695), Muhammad Shafqat Bashir (12261876), Shahzadi Mahpara (10196689), Salma Kausar (12078103), Rehmat Ullah (595875), Marian Brestic (584523), Muhammad Bilal (737265), Ehab A. A. Salama (12261879), Muhammad Arif (769250), Abdulrahman Al-Hashimi (11668632), Alanoud Alfagham (12261882)   +12 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Assessing the heat sensitivity of Urdbean (Vigna mungo L. Hepper) genotypes involving physiological, reproductive and yield traits under field and controlled environment

Frontiers in Plant Science, 2022
The rising temperatures are seriously impacting the food crops, including urdbean; hence efforts are needed to identify the sources of heat tolerance in such crops to ensure global food security. In the present study, urdbean genotypes were evaluated for
Shikha Chaudhary, Uday Chand Jha, Pronob J. Paul, P. V. Vara Prasad, Kamal Dev Sharma, Sanjeev Kumar, Debjyoti Sen Gupta, Parul Sharma, Sarvjeet Singh, Kadambot H. M. Siddique, Harsh Nayyar   +10 more
doaj   +1 more source

Physiological, developmental, and life-history traits datasets

, 2019
Multiple physiological, developmental, and life-history traits measurements in Drosophila melanogaster flies reared under various diet conditions, treated or not in order to remove gut ...
Youn Henry (4824060)
core   +1 more source

Pleiotropic Influence of DNA Methylation QTLs on physiological and aging traits

Epigenetics, 2023
Abstract DNA methylation is influenced by genetic and non-genetic factors. Here, we chart quantitative trait loci (QTLs) that modulate levels of methylation at highly conserved CpGs using liver methylome data from mouse strains belonging to the BXD Family.
Khyobeni Mozhui, Hyeonju Kim, Flavia Villani, Amin Haghani, Saunak Sen, Steve Horvath   +5 more
openaire   +3 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Effects of Downy Mildew Infection and Potassium on Growth and Physiological Traits of Greenhouse Cucumber

Agronomy
Both abiotic and biological stresses reduce the quality and quantity of cultivated plants. In order to observe the response of cucumber plants to potassium stress and cucumber downy mildew infestation, two different levels of downy mildew infestation, B0
Qiang Shi, Lu You, Yafei Wang, Xiaoxue Du, Tianhua Chen   +4 more
doaj   +1 more source

The mean comparison of physiological and biochemical studied traits for sickleweed populations using Duncan’s method.

, 2023
The mean comparison of physiological and biochemical studied traits for sickleweed populations using Duncan’s method.
Jaber Nasiri (5431601), Mojtaba Kordrostami (16412853), Mehdi Rahimi (5398259)   +2 more
core   +1 more source