Results 131 to 140 of about 591,200 (264)

Test-Retest Reliability of Physiological Variables During Submaximal Seated Upper-Body Poling in Able-Bodied Participants. [PDF]

Front Physiol, 2021
Ettema M, Brurok B, Baumgart JK.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Effect of exercise training on clinical and physiological variables in adults with myotonic dystrophy type 1: a systematic review and meta-analysis. [PDF]

J Neurol
Shetty S, Luo Y, Thomas A, Gamil K, Saxena I, Guha S, Vohra R, Lott DJ.   +7 more
europepmc   +1 more source

Influence of Menstrual Cycle or Hormonal Contraceptive Phase on Physiological Variables Monitored During Treadmill Testing. [PDF]

Front Physiol, 2021
Taipale-Mikkonen RS, Raitanen A, Hackney AC, Solli GS, Valtonen M, Peltonen H, McGawley K, Kyröläinen H, Ihalainen JK.   +8 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

AI and Internet of Things for Chronic Obstructive Pulmonary Disease Remote Monitoring: Systematic Review of Exacerbation Prediction and Key Physiological Variables. [PDF]

JMIR Med Inform
Montenegro M, Gielen J, Wang C, Vanrumste B, Ruttens D, Knevels R, Aerts JM.   +6 more
europepmc   +1 more source

Initial exploration of the discriminatory ability of the PetPace collar to detect differences in activity and physiological variables between healthy and osteoarthritic dogs. [PDF]

Front Pain Res (Lausanne), 2022
Rowlison de Ortiz A, Belda B, Hash J, Enomoto M, Robertson J, Lascelles BDX.   +5 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

The Impact of Competitive Fatigue on Physiological Variables in National Level Youth Swimmers. [PDF]

J Funct Morphol Kinesiol
López-Hernández A, Turner AP, Lam HKN, Simón-Piqueras JA, Muñoz de la Cruz V, González Ravé JM.   +5 more
europepmc   +1 more source

Proof-of-Concept and Test-Retest Reliability Study of Psychological and Physiological Variables of the Mental Fatigue Paradigm. [PDF]

Int J Environ Res Public Health, 2021
Brietzke C, Vinícius Í, Franco-Alvarenga PE, Canestri R, Goethel MF, Santos LER, Viana B, Santos TM, Pires FO.   +8 more
europepmc   +1 more source