Results 71 to 80 of about 591,200 (264)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
National Journal of Physiology, Pharmacy and Pharmacology, 2018 Background: Nonpharmacological interventions are gaining momentum in managing women in labor. Hence, dissemination of data on current evidence is mandatory, to persuade the professional midwives to equip themselves with complementary therapies to enhance
Mathew Jijimole +3 more
doaj +1 more source
Understanding octopus growth: patterns, variability and physiology
Marine and Freshwater Research, 2004 Octopuses are generally characterised by rapid non-asymptotic growth, with high individual variability. However, in situ octopus growth is not well understood. The lack of an ageing method has resulted in the majority of our understanding of octopus growth coming from laboratory studies.
Semmens, J.M. +6 more
openaire +2 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Health implications of radiological terrorism: Perspectives from Israel
Journal of Emergencies, Trauma and Shock, 2009 September 11 th events taught us, members of the medical community, that we need to prepared for the worst. Nuclear terror is no longer science fiction. Radiological weapons of mass terror come in three flavors: The first one is nuclear.
Hagby Moti +4 more
doaj
Heart rhythm characterization through induced physiological variables
Scientific Reports, 2017 Atrial fibrillation remains a major cause of morbi-mortality, making mass screening desirable and leading industry to actively develop devices devoted to automatic AF detection.
Jean-François Pons +6 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Environmental and physiological variables during the catching of broilers
Brazilian Journal of Poultry Science, 2015 The objective of this study was to determine the critical points of the operation of broiler catching for transport to the processing plant from animal and operational perspectives.
ML de V Queiroz +4 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source