Antihypertensive effect and the underlying mechanisms of action of phytolaccagenin in rat models
Clinical and Experimental Hypertension, 2022 Background Phytolaccagenin, a natural triterpenoid, is reported for various biological activities that indicate its potential role in the management of hypertension.
Abdul Jabbar Shāh +2 more
exaly +6 more sources
Investigation of phytochemical profiling and biological activities of methanol extract from Eryngium billardieri: antimicrobial, antibiofilm, and anthelmintic properties [PDF]
Frontiers in Plant ScienceThe genus Eryngium, belonging to the Umbelliferae family, comprises flowering plants with various pharmacological activities, including anti-inflammatory and antidiabetic properties. However, many of these activities lack scientific evaluation.
Mahdi Yaghoobi +9 more
doaj +5 more sources
Saponins from the roots of Chenopodium bonus-henricus L. with neuroprotective and anti-α-glucosidase activities [PDF]
Pharmacia, 2021 Six saponins of phytolaccagenin, bayogenin, medicagenic acid, 2β-hydroxygypsogenin, and 2β-hydroxyoleanoic acid from the roots of Chenopodium bonus-henricus L. were investigated for neuroprotective and anti-α-glucosidase activities.
Zlatina Kokanova-Nedialkova +2 more
doaj +5 more sources
Nectar robbing by bees affects the reproductive fitness of the distylous plant Tirpitzia sinensis (Linaceae). [PDF]
Ecol Evol, 2023 Nectar robbing could directly and indirectly decrease the female fitness of Tirpitzia sinensis, and different morphs have evolved different defense mechanisms in response to nectar robbing pressure. Abstract Nectar robbing can affect plant reproductive success directly by influencing female and male fitness, and indirectly by affecting pollinator ...
Wang X, Yao R, Lv X, Yi Y, Tang X.
europepmc +2 more sources
Chemical Composition of Cynanchum auriculatum Royle Ex Wight and Its Potential Role in Ameliorating Colitis. [PDF]
Food Sci NutrIn this study, the water extract of Cynanchum auriculatum Royle ex Wight root (CW) was prepared and its chemical composition was characterized using UPLC‐Q‐TOF‐MS. CW significantly alleviated DSS‐induced colitis in mice, as demonstrated by increased colon length, reduced disease activity index scores, and decreased histological damage in colon tissues.
Li S +10 more
europepmc +2 more sources
Inhibitory effect of esculentoside A on prostaglandin E(2) production from murine peritoneal macrophages and rabbit synovial cells in vitro. [PDF]
Mediators Inflamm, 1997 Esculentoside A (EsA) is a saponin isolated from the roots of Phytolacca esculenta. Previous experiments have shown that it has strong antiinflammatory effects. To investigate the mechanism of anti‐inflammatory effects of esculentoside A (EsA),[3H] arachidonic acid (AA) prelabelled murine macrophage and radioimmunoassay were used to test the effect of ...
Wang HB, Fang J, Zheng QY.
europepmc +2 more sources
Inhibitory effect of esculentoside A on tumour necrosis factor alpha production by human monocytes. [PDF]
Mediators Inflamm, 1996 Esculentoside A (EsA) is a saponin isolated from the roots of Phytolacca esculenta. Previous experiments have shown that it has strong anti‐inflammatory effects. Tumour necrosis factor (TNF) is a very important inflammatory mediator. It is known that there are two types of TNF—TNFα is from macrophages/monocytes and TNFβ is from activated lymphocytes ...
Wang HB, Fang J, Zheng QY.
europepmc +2 more sources
Effects of esculentoside A on turnour necrosis factor production by mice peritoneal macrophages. [PDF]
Mediators Inflamm, 1992 Esculentoside A (EsA) is a saponin isolated from the roots of Phytolacca esculenta. Previous experiments showed that it had strong anti‐inflammatory effects. Tumour necrosis factor (TNF) is an important inflammatory mediator. In order to study the mechanism of the anti‐inflammatory effect of EsA, it was determined whether TNF production from ...
Jun F, Yue ZQ, Bin WH, Wen JD, Hua YY.
europepmc +2 more sources
Antifungal Activity of Saponin-rich Extracts of and of the Sapogenins Obtained through Hydrolysis
Natural Product Communications, 2010 A saponin-rich extract of Phytolacca dioica L. berries, its acid hydrolysate, and its major aglycone, phytolaccagenin, were assayed for antifungal activity against ATCC standard cultures of Candida albicans and Cryptococcus neoformans , and against ...
Melina Di Liberto +7 more
doaj +1 more source
Bioactive Compounds and Antioxidant Properties with Involved Mechanisms of Eugenia involucrata DC Fruits. [PDF]
Antioxidants (Basel), 2022 Mannino G +6 more
europepmc +1 more source