Results 201 to 210 of about 10,466,988 (282)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Organic acids counteract the determinate root development induced by phosphate deprivation in <i>Arabidopsis thaliana</i>. [PDF]

Plant Signal Behav
Corona-Sánchez I, López-Bucio J, Villalobos-Escobedo JM, Vázquez-Fuentes S, Campos-García J, Cruz HR, López-Bucio JS.   +6 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Comparative efficacy of electric toothbrush technologies in plaque and gingivitis reduction: a network meta-analysis. [PDF]

Clin Oral Investig
Luo C, Chen N, Jing Q, Hu S, Wan S, Zhang S, Liu G, Li N, Zhao LY.   +8 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Mitotic Cdc42 waves encode PI(3,4)P₂ signaling and Golgi morphological state to control spindle scaling. [PDF]

Sci Adv
Fung SYS, Xiao S, Bao Y, Graham M, Su M, Liu X, Bewersdorf J, Wu M.   +7 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A prospective comparison of the diagnostic performance of a high b-value diffusion-weighted image-guided score versus PI-RADS v2.1 for transition zone prostate cancer. [PDF]

Front Oncol
Li K, Xu T, Yan X, Mi S, Jiang M, Chen L, Kuang F.   +6 more
europepmc   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

<i>Lotus japonicus</i> VIH2 is an inositol pyrophosphate synthase that regulates arbuscular mycorrhiza. [PDF]

Sci Adv
Raj K, Gaugler V, Lu M, Schädel M, Gaugler P, Grothaus CMM, Jochimsen UA, Makris A, Bartsch SM, Frentzen AM, Liu G, Harings M, Fiedler D, Jessen HJ, Schaaf G, Ried-Lasi MK.   +15 more
europepmc   +1 more source