Results 241 to 250 of about 662,858 (278)

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Exploring an azo-uracil based nickel(ii) complex for anticancer and phosphatase like activities. [PDF]

RSC Adv
Ghosh S, Daripa S, Shyam T, Hira SK, Das D.   +4 more
europepmc   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Flatback Deformity and Stiff Pelvic Mobility Alter the Optimal Cup Anteversion After Total Hip Arthroplasty: Insights from 3D-to-2D Model-Image Registration Analysis. [PDF]

JB JS Open Access
Konishi T, Hamai S, Higaki H, Kawahara S, Yamaguchi R, Motomura G, Utsunomiya T, Kitamura K, Yoshino S, Ikebe S, Nakao Y, Inoue T, Uehara W, Nakashima Y.   +13 more
europepmc   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

Investigating the Role of Miscibility in Hydrogenated Dicyclopentadiene Resin/Polymer Blends: A Molecular Dynamics Study. [PDF]

Polymers (Basel)
Rissanou AN, Ghanta R, Doxastakis M, Harmandaris V.   +3 more
europepmc   +1 more source

Emergence of Frank-Kasper Phases from Chemically Simple Block Copolymer: Poly(ethylene oxide)-<i>block</i>-polyisoprene and Its Dry-Brush Blends. [PDF]

Macromolecules
Huang ZE, Chuang YC, Lin YC, Sung YC, Luo KW, Tsai JC, Chen HL.   +6 more
europepmc   +1 more source

Hypolipidemics reduce the rate of Alzheimer's disease development and dementia progression: A cohort study linked with genetic and neuropathological analyses. [PDF]

J Prev Alzheimers Dis
Sternberg Z, Podolsky RE, Yu J, Hua S, Halvorsen S, Schaller BJ.   +5 more
europepmc   +1 more source

A novel adaptive neuro-fuzzy and adaptive proportional resonant control scheme for PMSM based electric vehicle applications. [PDF]

Sci Rep
Sangeetha E, Ramachandran VP.
europepmc   +1 more source