Results 51 to 60 of about 5,002 (241)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The Omega Rule is $\mathbf{\Pi_{1}^{1}}$-Complete in the $\lambda\beta$-Calculus [PDF]

open access: yesLogical Methods in Computer Science, 2009
In a functional calculus, the so called \Omega-rule states that if two terms P and Q applied to any closed term N return the same value (i.e. PN = QN), then they are equal (i.e. P = Q holds).
Benedetto Intrigila, Richard Statman
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Just Fast Keying in the Pi Calculus [PDF]

open access: yesACM Transactions on Information and System Security, 2004
JFK is a recent, attractive protocol for fast key establishment as part of securing IP communication. In this paper, we formally analyze this protocol in the applied pi calculus (partly in terms of observational equivalences and partly with the assistance of an automatic protocol verifier).
Abadi, M., Blanchet, B., Fournet, C.
openaire   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

A Sorted Semantic Framework for Applied Process Calculi [PDF]

open access: yesLogical Methods in Computer Science, 2016
Applied process calculi include advanced programming constructs such as type systems, communication with pattern matching, encryption primitives, concurrent constraints, nondeterminism, process creation, and dynamic connection topologies.
Johannes Borgström   +4 more
doaj   +1 more source

Parallel computing with the Pi-calculus [PDF]

open access: yesProceedings of the sixth workshop on Declarative aspects of multicore programming, 2011
To tackle the multi-core programming challenge, we investigate the design and implementation of concurrency-oriented programming languages. Our approach mimics the evolution from lambda-calculi to functional programming languages, but with the pi-calculus as a starting point.
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Divergence and unique solution of equations [PDF]

open access: yesLogical Methods in Computer Science, 2019
We study proof techniques for bisimilarity based on unique solution of equations. We draw inspiration from a result by Roscoe in the denotational setting of CSP and for failure semantics, essentially stating that an equation (or a system of equations ...
Adrien Durier   +2 more
doaj   +1 more source

A π-calculus with explicit substitutions

open access: yesTheoretical Computer Science, 1996
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
FERRARI, GIAN-LUIGI   +2 more
openaire   +4 more sources

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