Survival Comes at a Cost: A Coevolution of Phage and Its Host Leads to Phage Resistance and Antibiotic Sensitivity of Pseudomonas aeruginosa Multidrug Resistant Strains [PDF]
The increasing ineffectiveness of traditional antibiotics and the rise of multidrug resistant (MDR) bacteria have necessitated the revival of bacteriophage (phage) therapy. However, bacteria might also evolve resistance against phages.
Sarshad Koderi Valappil +15 more
doaj +6 more sources
Assessing the practicality of using freely available AI-based GPT tools for coach learning and athlete development [PDF]
This study represents one of the initial efforts to analyse a coach-athlete conversational dataset using freely available GPT tools and a pre-determined, context-specific, prompt-based analyses framework (i.e., R2-PIASS).
Katherine A. O'Brien, Sarah Prentice
doaj +3 more sources
Design a variety of cation exchange hydrogel resins using gamma irradiation to remove hard/scale metal cations from saline water under different circumstances [PDF]
This study aims to develop a series of cation exchange hydrogel resins via gamma irradiation technique through copolymerizing styrene sodium sulfonate with three acrylamide derivatives (designated as poly(X-co-styrene sodium sulfonate), where X refers to
Sherif A. F. Romeeh +5 more
doaj +3 more sources
SUMO3 modification by PIAS1 modulates androgen receptor cellular distribution and stability [PDF]
Background Abnormal reactivation of androgen receptor (AR) signaling in castration-resistant prostate cancer (CRPC) mainly results from overexpression and down-regulation of AR. Sumoylation of AR can influence its function.
Nanyang Yang +7 more
doaj +3 more sources
A novel role of Krüppel-like factor 8 in DNA repair in breast cancer cells. [PDF]
Background: KLF8 is a cancer-promoting transcription factor. Results: KLF8 inhibits DNA damage in breast cancer cells. Conclusion: KLF8 is a novel effector of the PARP-1 and DNA-PK DNA damage response pathways.
Lu H +9 more
europepmc +5 more sources
In current study, different feeding levels of Moringa oleifera formulated diet was compared to analyze the growth performance, feed conversion ratio, feed conversion efficiency and gut microbiology of Oreochromis niloticus.
M. U. Taj +10 more
doaj +2 more sources
Oncostatin M (OSM) is linked with multiple biological responses including growth and differentiation. Previous reports showed inhibitory effects of OSM in tumor progression while others showed promoting effects. The dual role of OSM in the development of various cancers is still unclear. We previously described OSM-mediated SLUG suppression, leading to
Pan, Chih-Ming +4 more
openaire +4 more sources
Age-associated myeloid malignancies - the role of STAT3 and STAT5 in myelodysplastic syndrome and acute myeloid leukemia. [PDF]
The increase in the aging population has resulted in the rise of age‐related disorders, including MDS and AML. The JAK–STAT pathway is essential for several cellular functions in the HSPCs. Deregulation of the STAT3/5 signaling may occur at several pathway stages (indicated by exclamation points) and has been associated with MDS and AML development ...
Fasouli ES, Katsantoni E.
europepmc +2 more sources
A implantação do PIASS no estado da Bahia
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V. Formigli
openaire +2 more sources
Este artigo relata a implantação do Programa de Saúde da Família no Estado de São Paulo desde seu início até o ano de 2002. São mencionados como antecedentes importantes outros programas do Ministério da Saúde, como o PIASS (1976-1979), o PACS (1991) e o
Jose da Silva Guedes +2 more
doaj +2 more sources

