Results 91 to 100 of about 15,257 (215)

Evaluating digital cognitive tests for clinical use in Alzheimer's disease: A novel framework and scoping review

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract Mild cognitive impairment (MCI), a prodromal stage of Alzheimer's disease (AD), remains undiagnosed in > 90% of individuals, delaying access to timely evaluation and interventions. Self‐administered digital cognitive assessments (SA‐DCAs) offer scalable approaches for early detection, yet their real‐world validation and clinical readiness ...
Harald Hampel, Yosuke Nakamura, Joanne Bell, Suzanne Hendrix, Miron Derchansky, Bruno B. Montezano, Luke E. Stoeckel, Stefan Teipel, Deanna R. Willis, Jeffrey L. Cummings, Bryan R. Cobb   +10 more
wiley   +1 more source

Characterization of [18F]SMBT‐1 binding substrates in Alzheimer's disease and related disorders: A postmortem biochemical and immunohistochemical study

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Neuroimaging studies report associations of amyloid beta (Aβ) positron emission tomography (PET) with [18F](S)‐(2‐methylpyrid‐5‐yl)‐6‐[(3‐fluoro‐2‐hydroxy)propoxy]quinoline ([18F]SMBT‐1), a novel reactive astrogliosis surrogate radiotracer with high affinity for monoamine oxidase B (MAO‐B) in Alzheimer's disease (AD).
Eric E. Abrahamson, Julia K. Kofler, Oscar L. Lopez, Anne D. Cohen, Alexandra Gogola, Howard J. Aizenstein, Thomas K. Karikari, Elliott J. Mufson, Victor L. Villemange, Milos D. Ikonomovic   +9 more
wiley   +1 more source

The relationships between recovery and teachers' exhaustion and performance: mediational role of work-related self-efficacy

Medycyna Pracy
Background The aim of the study was to better understand the process through which recovery leads to teachers’ exhaustion and performance. The direct and the indirect, i.e., mediated by teacher’ work-related self-efficacy, effects of recovery on ...
Łukasz Baka, Łukasz Kapica, Elżbieta Łastowiecka-Moras   +2 more
doaj   +1 more source

Sex specificity of resistance to caTAUstrophe

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION As amyloid beta (Aβ) accumulates, tau pathology spreads beyond medial temporal lobe (MTL) into neocortical (NEO) regions, though some older adults resist this progression, or what we call here “caTAUstrophe.” Given previous evidence of higher tau levels in women, we tested how tau resistance presented in men and women separately ...
Maria Carrigan, Colin Birkenbihl, Hannah M. Klinger, Oliver Langford, Gillian T. Coughlan, Mabel Seto, Jane A. Brown, Annie Li, Madison Cuppels, Michael Properzi, Jasmeer Chhatwal, Julie Price, Aaron Schultz, Dorene Rentz, Rebecca Amariglio, Harm J. Krugers, Rik Ossenkoppele, Keith Johnson, Reisa Sperling, Timothy J. Hohman, Michael Donohue, Rachel F. Buckley   +21 more
wiley   +1 more source

Optimized plasma p‐tau217 and p‐tau217/Aβ42 cutoffs enhance detection of pre‐clinical Alzheimer's disease across diverse participants

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Plasma p‐tau217 and p‐tau217/Aβ42 reliably identify non‐Hispanic White individuals with symptomatic and pre‐clinical AD. However, performance across ethnoracially diverse groups remains unknown. METHODS Cognitively normal Black, Hispanic, and non‐Hispanic White participants completed cognitive evaluations, brain magnetic resonance
Yoav D Piura, Paula A Aduen, Leah Schecter, Manoj K Jain, Alicia Algeciras‐Schimnich, Daniel J Figdore, Joshua Bornhorst, Ronald C Petersen, Clifford R Jack Jr, Neill R Graff‐Radford, Christian Lachner, Gregory S Day   +11 more
wiley   +1 more source

An IoT‐Enabled Growth Management System With Deep Learning‐Based Monitoring for Volvariella volvacea Mushroom Cultivation in Controlled Environments

Applied Research, Volume 5, Issue 4, August 2026.
An IoT‐enabled environmental control system integrated with a YOLOv8 deep learning model enables automated cultivation and real‐time growth‐stage monitoring of Volvariella volvacea. The proposed system improves environmental stability, achieves 93.12% growth‐stage classification accuracy, and enhances cultivation reliability, productivity, and ...
Husna Hamza, Julie Roslita Rusli, Aiman Hambali Bin Amran, Muhammad Safwan bin Saad, Izanoordina Ahmad, Rohaida Hussain, Noor Amalina Ramli, Ida Bagus Irawan Purnama, dan I Nyoman Kusuma Wardana   +8 more
wiley   +1 more source

Just Transition Toward Clean Energy Access With Focus on Lead‐Based Perovskite Solar Cell Technology: Lessons, Experiences, and Future Perspectives

Global Challenges, Volume 10, Issue 8, August 2026.
To intentionally mitigate energy poverty in underserved communities, advanced perovskite energy technologies such as lead‐based perovskite solar cells are necessary. However, in future deployment of these materials, energy justice, equity, inclusivity and environmental sustainability must be taken into account.
Benjamin K. Korir, George G. Njema, Mojeed A. Agoro, Thembinkosi Donald Malevu, Joshua K. Kibet   +4 more
wiley   +1 more source

Capital humano y ciencia: la inversión más rentable para Paraguay

Revista Investigaciones y Estudios de la UNA
Paraguay enfrenta undesafío estructural en ciencia, tecnología e innovación (CTI).Históricamente, el país ha destinado menos del 0,2% del Producto Interno Bruto (PIB) a Investigación y Desarrollo (I+D), un nivel muy inferior al promedio ...
Meza Ocampos, Griselda Asunción, Silvero Arévalos, José Manuel   +1 more
doaj   +1 more source

Multimodel Diffusion MRI Signatures in Atypical Parkinsonian Disorders

Human Brain Mapping, Volume 47, Issue 11, 01 August 2026.
We implemented a diffusion MRI framework to analyze clinically compatible multishell data across 123 participants, including controls, Parkinson's disease (PD), corticobasal syndrome (CBS), and progressive supranuclear palsy Richardson's syndrome (PSP‐RS). Diffusion models included DTI, free‐water elimination (FWE), NODDI, and fixel‐based analysis (FBA)
Yuqi Tian, Farwa Ali, Mary M. Machulda, Val. J. Lowe, Keith A. Josephs, Jennifer L. Whitwell   +5 more
wiley   +1 more source

MOF/MXene Composites for Advanced Electrochemical Energy Storage: Transitioning From Laboratory Research to Practical Application

Rare Metals, Volume 45, Issue 8, August 2026.
ABSTRACT Composites of metal–organic frameworks (MOFs)/two‐dimensional transition metal carbides/nitrides (MXene) have been widely recognized as promising electrode materials for advanced electrochemical energy storage systems due to their synergistic structural advantages and tunable electrochemical properties.
Wenjun Zhu, Ziming Wang, Guanrong Wu, Xinyong Tao, Fanxing Bu, Jianmin Luo   +5 more
wiley   +1 more source