Results 51 to 60 of about 144,706 (301)

Pacman Percolation and the Glass Transition [PDF]

open access: yes, 2013
We investigate via Monte Carlo simulations the kinetically constrained Kob-Andersen lattice glass model showing that, contrary to current expectations, the relaxation process and the dynamical heterogeneities seems to be characterized by different time ...
Ciamarra, Massimo Pica   +2 more
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Pica practices of pregnant women in Nairobi Kenya

open access: yesInternational Journal of Medicine and Health Development, 2009
Aim: To establish the prevalence of pica behaviour during pregnancy; to identify the substances commonly ingested and their prevalence; and to determine the characteristics of women who reported practicing pica.
Ngozi P Ogbonnaya, Blassio Omuga
doaj  

Comparison of pica in breastfeeding versus artificial feeding in children 2 years of age or younger

open access: yesMedical Journal of Babylon, 2018
Background: Pica is the daily compulsive eating of food or nonfood items not part of one's habitual diet or preferences, which is inappropriate to the developmental level.
Sijal Fadhil F. Al-Joborae   +1 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Geophagia: A case series

open access: yesIndustrial Psychiatry Journal, 2021
Geophagia, a form of pica, is often associated with iron and zinc deficiency. However, a number of environmental, cultural, and psychological factors are also implicated. Pica in children is common with those having intellectual disability. In adults, it
Ichpreet Singh   +4 more
doaj   +1 more source

Role of cell deformability in the two-dimensional melting of biological tissues

open access: yes, 2018
The size and shape of a large variety of polymeric particles, including biological cells, star polymers, dendrimes, and microgels, depend on the applied stresses as the particles are extremely soft.
Ciamarra, Massimo Pica, Li, Yan-Wei
core   +1 more source

$SU(2)$ Gauge Theory with Two Fundamental Flavours: Scalar and Pseudoscalar Spectrum [PDF]

open access: yes, 2016
We investigate the scalar and pseudoscalar spectrum of the $SU(2)$ gauge theory with $N_f=2$ flavours of fermions in the fundamental representation using non perturbative lattice simulations.
Arthur, Rudy   +4 more
core   +3 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

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