Results 151 to 160 of about 25,215 (225)

Development and analytical validation of a targeted short‐read next generation sequencing‐based pharmacogenetic panel for comprehensive variant detection

British Journal of Pharmacology, Volume 183, Issue 16, Page 4735-4760, August 2026.
Abstract Background and Purpose Genomic profiling of patients for genetic variants that modify the effect of specific medications has many benefits, including the possibility of avoiding toxicities and ensuring an adequate effect of the medication. Our intention was to develop a comprehensive, high‐quality pharmacogenetic test panel for clinical use ...
Anna Gréen, Nils Johan Fredriksson, Michael Andresen, Jon Jonasson, Malin Lindqvist Appell, Henrik Gréen   +5 more
wiley   +1 more source

Early detection and subtyping of gastric cancer: A cell-free DNA fragmentome-based liquid biopsy method. [PDF]

iScience
Chen Y, Liao H, Liu Y, Luo L, Jin J, Hou D, Liu W, Zhang H, He B, Luo M, Liu W, Lin Z, Xu S.   +12 more
europepmc   +1 more source

Biomarker‐Based Diagnosis and Care Pathways for Alzheimer's Disease in the Era of Disease‐Modifying Treatments: A Consensus Statement by Belgian Experts

European Journal of Neurology, Volume 33, Issue 8, August 2026.
ABSTRACT Background The recent approval of disease‐modifying therapies (DMTs) for early Alzheimer's disease (AD) marks a major shift in clinical practice. Biomarker confirmation of amyloid pathology is now required alongside clinical assessment, and blood‐based tests are improving accessibility.
Tim Van Langenhove, Sara Van Mossevelde, Marijke Miatton, Jan De Lepeleire, Rose Bruffaerts, Jean Christophe Bier, Kurt Segers, Jurn Verschraegen, Mirko Petrovic, Manfredi Ventura, Haroun Jedidi, Ingo Beyer, Eric Mormont, Rik Vandenberghe, Aline Delva, Christian Gilles, Donatienne Van Weehaeghe, Gaëtane Picard, Peter De Deyn, Mélanie Strauss, Evert Thiery, Eric Salmon, Gert Cypers, Joris Vlaemynck, Katrin Gillis, Jan Versijpt, Maria Bjerke, Anne Sieben, Bernard Hanseeuw, Sebastiaan Engelborghs, Olivier Deryck, on behalf of the BeDeCo members   +31 more
wiley   +1 more source

Stress Cardiac Magnetic Resonance Ischemia Burden and Cardiovascular Events: Post-Hoc Analysis From the ISCHEMIA Trial. [PDF]

JACC Cardiovasc Imaging
Kwong RY, Heydari B, Abbasi S, Mongeon FP, Marcotte F, Friedrich M, Shaw LJ, Xu Y, Anthopolos R, Bekeredjian R, Monti L, Selvanayagam J, Lesiak M, Picard MH, Berman DS, Bangalore S, Spertus JA, Stone GW, Boden WE, Min J, Mancini GBJ, Leipsic J, Budoff M, Hague C, Hochman JS, Maron DJ, Reynolds HR, ISCHEMIA Research Group.   +27 more
europepmc   +1 more source

Divergent Thermal Reaction Norms of the Spontaneous Mutation Rate Among Populations of Chironomus riparius

Molecular Ecology, Volume 35, Issue 15, August 2026.
ABSTRACT The germline mutation rate μ is a fundamental evolutionary parameter, yet its plasticity in response to environmental factors, particularly temperature, remains poorly understood. While often modelled as a species‐specific constant, we tested whether μ evolves in response to local thermal regimes.
Markus Pfenninger, Maria Esther Nieto‐Blazquez, Burak Bulut   +2 more
wiley   +1 more source

Ionic Conductivity of Composite Polymer Electrolyte: Clarifying the Role of the Interface with Nonconductive Particles. [PDF]

ChemSusChem
Navallon G, Monaco F, Märker K, Cloetens P, Drnec J, Atkins D, Picard L, Lyonnard S.   +7 more
europepmc   +1 more source

Spatial inference of ancestor locations suggests northern refugia for canopy‐forming kelps in the Pacific Northwest

New Phytologist, Volume 251, Issue 4, Page 2248-2265, August 2026.
Population genetic structure in the Pacific Northwest for (a–c) Nereocystis and (d–f) Macrocystis. Summary Pockets of the formerly glaciated Pacific coastline of North America likely remained ice‐free throughout the Last Glacial Maximum (LGM). These areas may have served as refugia for terrestrial species, but less is known about their role in the ...
Jordan B. Bemmels, Kristy J. Kroeker, Stephen R. Palumbi, Rachael A. Bay, Kristen M. Gruenthal, Sandra C. Lindstrom, Matthew M. Osmond, Gregory L. Owens   +7 more
wiley   +1 more source

Clinical Features and Biomarkers Associated With Intensive Care-Dependent Refractory NMDAR Encephalitis: A Retrospective Cohort Study. [PDF]

Neurol Neuroimmunol Neuroinflamm
Elosua-Bayes I, Dumez P, Benaiteau M, Ciano-Petersen NL, Farina A, Villagrán-García M, Peter E, Birzu C, Fourier A, Aubart M, Picard G, Do LD, Rogemond V, Goncalves D, Psimaras D, Honnorat J, Joubert B.   +16 more
europepmc   +1 more source

On the positivity and integrality of coefficients of mirror maps

Bulletin of the London Mathematical Society, Volume 58, Issue 8, August 2026.
Abstract We present natural conjectural generalisations of the ‘positivity and integrality of mirror maps’ phenomenon, encompassing the mirror maps appearing in the Batyrev–Borisov construction of mirror Calabi–Yau complete intersections in Fano toric varieties as a special case.
Sophie Bleau, Nick Sheridan
wiley   +1 more source