Results 211 to 220 of about 698,086 (300)

Reshaping study design for faster extrapolation‐based drug approval in pediatric inflammatory bowel diseases: An ESPGHAN–NASPGHAN position paper

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Children with inflammatory bowel diseases (IBD) have limited access to the available advanced therapies, given the lengthy gap between adult and pediatric approval. We aimed to review key hurdles for pediatric trials and recommend practical solutions.
Dan Turner   +21 more
wiley   +1 more source

Comparing the Last Interglacial (MIS 5e) with the present interglacial period (MIS 1) using a multidimensional functional diversity analysis: The marine molluscs from Santa Maria Island (Azores Archipelago, central Atlantic) as a case study

open access: yesJournal of Quaternary Science, EarlyView.
ABSTRACT Marine fossil records hold outstanding importance for ecological, evolutionary and biogeographical studies. Santa Maria Island in the Azores Archipelago (central Atlantic) features a remarkable marine fossil record spanning from the Pliocene to recent times.
Sérgio P. Ávila   +16 more
wiley   +1 more source

OpenDosimeter: Open hardware personal X-ray dosimeter. [PDF]

open access: yesCommun Eng
Ger N   +10 more
europepmc   +1 more source

Automated Imaging of Cultured Bacteria in Picoliter Droplets by Coherent Anti‐Stokes Raman Scattering and Two‐Photon Excited Fluorescence Microscopy

open access: yesJournal of Raman Spectroscopy, EarlyView.
We present an automated system that combines an image‐based fuzzy logic controller for precise positioning of microfluidic picoliter droplets with nonlinear microscopy, using CARS and TPEF modalities for detailed analysis of droplet composition. Time series and z‐stack images of E. coli, B. subtilis, and M. arborescens were recorded.
Fabian Ott   +6 more
wiley   +1 more source

Unravelling the Major Cardiovascular Risks of Systemic Psoriasis Medications: A Literature Systematic Review

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Psoriasis is a chronic inflammatory dermatological condition associated with an elevated risk of cardiovascular events (CVEs). Systemic therapies have transformed disease management, but their cardiovascular (CV) safety profiles remain incompletely understood and inconsistently reported.
Mai Thi Hoai Son   +10 more
wiley   +1 more source

Is There Benefit in Treating Traction Alopecia With Minoxidil? A Systematic Review

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Traction alopecia (TA) is common condition. Although no treatment guidelines exist, minoxidil can be adjunctively added to behavioural modification strategies. Objectives This systematic review aimed to evaluate the impact of adjunctive minoxidil on the severity of TA.
Husna Moola   +3 more
wiley   +1 more source

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