Results 221 to 230 of about 698,086 (300)

Oxymatrine Inhibits Epithelial‐Mesenchymal Transition to Alleviate Airway Remodeling in Chronic Obstructive Pulmonary Disease by Suppressing the TGF‐β1/Smad Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study explored the therapeutic efficacy of oxymatrine (OMT, C15H24N2O2) in a murine model of cigarette smoke (CS)‐induced chronic obstructive pulmonary disease (COPD) and elucidated its underlying mechanisms. A COPD model was established in mice through prolonged exposure to CS, followed by intraperitoneal administration of OMT (50 mg/kg)
Shuang Zhou, Ju‐Xiang Zhu, Jing Li
wiley   +1 more source

The PICO Puzzle: Can Public Data Predict EU HTA Expectations for All EU Countries? [PDF]

J Mark Access Health Policy
Eberle K, Hagemann LM, Schweitzer MK, Justl M, Maurer J, Carls A, Reuter EM.   +6 more
europepmc   +1 more source

Quadriceps, hamstring and patella tendon autografts for primary anterior cruciate ligament reconstruction demonstrate similar clinical outcomes, including graft failure, joint laxity and complications: A systematic review with meta‐analysis of randomised controlled trials

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Graft failure following anterior cruciate ligament reconstruction (ACLR) remains a significant challenge, driving discussion for optimal graft choice. Traditionally, hamstring tendon (HT) and bone‐patella tendon‐bone (BPTB) autografts have been favoured for ACLR. Recently, quadriceps tendon (QT) usage has increased.
Ty White, Matthew Castro, Lucas Antonio, Wayne Hing, Francois Tudor, Larissa Sattler   +5 more
wiley   +1 more source

Identifying Research Gaps in the Diagnosis and Treatment of Hypertension: Evidence from a Guideline Update. [PDF]

Iran J Nurs Midwifery Res
Sarrafzadegan N, Shahidi S, Kholenjani FB.   +2 more
europepmc   +1 more source

Reliable labels, uncertain meaning: Classifications for medial meniscus posterior root tears lack consensus and arthroscopy‐anchored accuracy

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
ABSTRACT Purpose Multiple, nonharmonised classification systems exist for posterior medial meniscus root tears (PMMRT), yet their diagnostic accuracy and observer reliability remain unclear. This PRISMA‐2020 systematic review aimed to catalogue available PMMRT classifications and to summarise accuracy and reliability metrics.
Michelangelo Palco, Gabriele Giuca, Filippo Familiari, Danilo Leonetti, Robert F. LaPrade, Roberto Simonetta   +5 more
wiley   +1 more source

Cardiopulmonary Resilience in Highly Active Individuals: Pre-Post COVID-19 Cardiopulmonary Exercise Testing Analysis. [PDF]

Arq Bras Cardiol
Braga F, Espinosa G, Monteiro A, Milani M, Paiva J, Milani JGPO, Franzoni L, Stein R, Cipriano G, Gurgel JL, Mourilhe-Rocha R.   +10 more
europepmc   +1 more source

Association between walking gait biomechanical changes after anterior cruciate ligament injury or reconstruction and the development of osteoarthritis: A systematic review

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Anterior cruciate ligament (ACL) injury and reconstruction significantly increase the risk of knee osteoarthritis (OA). Biomechanical alterations during walking are frequently suggested contributors to OA development. This systematic review aims to determine the association between walking gait biomechanical changes following ACL ...
Jérôme Riera, Mattéo Campion, Thomas Néri, Alexandre J. M. Rambaud, Noémie C. Duclos   +4 more
wiley   +1 more source

Gutflix 'How to Develop Guidelines' Series. [PDF]

United European Gastroenterol J
Yusuf Z, Sayers AE, Maeda Y.
europepmc   +1 more source

Periprosthetic joint infection risk is comparable between unicompartmental knee arthroplasty to total knee arthroplasty conversion and primary total knee arthroplasty: A systematic review and meta‐analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Unicompartmental knee arthroplasty (UKA) offers benefits over total knee arthroplasty (TKA), but some studies indicated higher revision rates, often involving conversion to TKA. The infection risk associated with UKA to TKA conversion compared to primary TKA is not definitively established.
Maximilian Budin, Matthew De Ruyter, Zachary Christopher Lum, Jürgen Slapar, Jochen Gerhard Hofstaetter, Georg Hauer, Andreas Leithner, Patrick Sadoghi   +7 more
wiley   +1 more source