Results 221 to 230 of about 699,785 (299)

Parkinson's Disease Patient‐Specific Striatum Organoids Show Hallmarks of Increased Inflammation

Movement Disorders, EarlyView.
Abstract Background Dopaminergic neurons from the substantia nigra pars compacta project their axons into the dorsal striatum, forming the nigrostriatal pathway. In Parkinson's disease (PD), dopaminergic terminals degenerate in the striatum, leading to dopamine depletion, which in turn causes alterations in the basal ganglia circuits that are essential
Kyriaki Barmpa, Claudia Saraiva, Alise Zagare, Mona Tuzza, Joseph Longworth, Elisa Zuccoli, Katrin Hufnagel, Florian Skwirblies, Ronny Schmidt, Dirk Brenner, Christoph Schröder, Jens C. Schwamborn   +11 more
wiley   +1 more source

ERS/EULAR clinical practice guidelines for connective tissue disease-associated interstitial lung disease. [PDF]

Eur Respir J
Antoniou KM, Distler O, Gheorghiu AM, Moor CC, Vikse J, Bizymi N, Galetti I, Brown G, Bargagli E, Allanore Y, Corte TJ, Dieudé P, Cottin V, Fisher BA, Fabre A, Giles JT, Kreuter M, Lundberg IE, Poletti V, Maurer B, Renzoni EA, Müller-Ladner U, Strek ME, Sverzellati N, Studenic P, Mohammed J, Nagavci B, Stamm T, Tonia T, Crestani B, Hoffmann-Vold AM.   +30 more
europepmc   +1 more source

From Design to Implementation: NursingUP® Board Game for Positive Nursing Practice Environments

Research in Nursing &Health, EarlyView.
ABSTRACT Positive nursing practice environments are fundamental to patient safety, care quality, and nurses’ well‐being. However, few structured and evidence‐based interventions have been developed to actively strengthen these environments and foster collaboration among nursing teams.
Soraia Cristina de Abreu Pereira, Cintia Silva Fassarella, Olga Maria Pimenta Lopes Ribeiro   +2 more
wiley   +1 more source

Digital psychosocial follow-up for survivors of childhood critical illness: protocol for a systematic literature review. [PDF]

Syst Rev
Hagen MH, Jaccheri L, Papavlasopoulou S, Hartvigsen G, Sæter T.   +4 more
europepmc   +1 more source

Safety and Efficacy of Glucagon‐Like Peptide‐1 Receptor Agonists Use in Elderly People With Obesity—A Meta‐Analysis

Obesity, EarlyView.
ABSTRACT Objective This meta‐analysis evaluates the safety and efficacy of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) for the treatment of older adults with obesity compared to younger individuals. Methods A systematic review was conducted following PRISMA guidelines (PROSPERO CRD420251074381).
Inês Rego de Figueiredo, Filipa Sofia Simas, Angela Ghiletchi, João Oliveira Torres, José Silva‐Nunes   +4 more
wiley   +1 more source

Leukocyte-rich versus leukocyte-poor platelet-rich plasma for Osteoarthritis: A systematic review. [PDF]

Regen Ther
Martín-Vega M, Gómez-Carrión Á, Zaragoza-García I, Ortuño-Soriano I, Marcelino-Argemi A, Sanz-Wozniak P, Saludes-Llamas R, Sánchez-Gómez R.   +7 more
europepmc   +1 more source

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC‐MS

PROTEOMICS, EarlyView.
ABSTRACT Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are limited to quantify or discover new subcellular structures.
Rachel A. Victor, Austin Lipinski, Paul R. Langlais, Jacob C. Schwartz   +3 more
wiley   +1 more source

From Realism to Learner Engagement: Rethinking Fidelity in Simulation-Based Education.

JMIR Med Educ
Pico J, Evain JN, Aron C, Martin G, Cruz-Panesso I, Georgescu LM, Tanoubi I.   +6 more
europepmc   +1 more source