Results 261 to 270 of about 5,000,063 (295)

Quantitative probing of reactive oxygen species and their selective degradation on contaminants in peroxymonosulfate-based process enhanced by picolinic acid.

Journal of Hazardous Materials, 2023
Jiayin Yan, Huihui Liu, C. Dou, Yanlin Wu, W. Dong   +4 more
semanticscholar   +1 more source

3-((carboxymethyl)thio)-picolinic acid - A novel inhibitor of phosphoenolpyruvate carboxykinase.

Biochemistry, 2019
Phosphoenolpyruvate carboxykinase (PEPCK) activity has traditionally been characterized for its role as the first committed step of gluconeogenesis.
M. McLeod, Anthony P Krismanich, A. Assoud, G. Dmitrienko, T. Holyoak   +4 more
semanticscholar   +1 more source

Role of zinc in blockade of excitotoxic action of quinolinic acid by picolinic acid

Amino Acids, 1998
This study examined whether picolinic acid (PIC) inhibits quinolinic acid (QUIN)-induced excitotoxicity through zinc chelation. Injection of QUIN into the nucleus basalis magnocellularis significantly depleted cortical choline acetyltransferase activity 7 days post injection and PIC inhibited this response. Zinc augmented the QUIN- but not NMDA-induced
Richard J. Beninger, Roland J. Boegman, Khem Jhamandas, S. Flesher   +3 more
openaire   +2 more sources

Electronic and Crystal Packing Effects in Terms of Static and Kinetic Force Field Features: Picolinic Acid N-Oxide and Methimazole

Crystal Growth & Design, 2023
S. Kartashov, S. A. Shteingolts, A. Stash, V. Tsirelson, R. Fayzullin   +4 more
semanticscholar   +1 more source

Picolinic acid as a matrix for laser mass spectrometry of nucleic acids and proteins

Rapid Communications in Mass Spectrometry, 1994
AbstractWe found that picolinic acid is a very good matrix for matrix‐assisted laser desorption/ionization (MALDI) time‐of‐flight mass spectrometry of oligonucleotides, proteins and tRNA. Among the oligonucleotides, picolinic acid was shown to be effective for homo‐oligonucleotides, d(G)40 and d(C)60, and for mixed‐base oligonucleotides up to 190 bases.
L. Y. Chág, C. H. Chen, Kai Tang, K. B. Jacobson, N. I. Taranenko, Steve L. Allman   +5 more
openaire   +3 more sources

Metal-Free Decarboxylative Alkoxylation of 2-Picolinic Acid and Its Derivatives with Cyclic Ethers: One Step Construction of C-O and C-Cl Bonds.

Organic Letters, 2018
A new strategy for the metal-free decarboxylative alkoxylation of 2-picolinic acid and its derivatives is described. The three-component reaction of 2-picolinic acid or its derivatives, cyclic ethers, and tBuOCl proceeded smoothly in the presence of a ...
Xiaoqiang Yu, M. He, Jianglin Wu, Chuancheng Zhou, Xiujuan Feng, Yoshinori Yamamoto, M. Bao   +6 more
semanticscholar   +1 more source

Exploring the in vitro anticancer activities of Re(I) picolinic acid and its fluorinated complex derivatives on lung cancer cells: a structural study

JBIC Journal of Biological Inorganic Chemistry, 2022
Mabu L. Matlou, F. Malan, S. Nkadimeng, L. Mcgaw, V. J. Tembu, A. Manicum   +5 more
semanticscholar   +1 more source

Architectured Fe3Pd2(OH)2[picolinic acid]8(H2O)4 Hybrid Nanorods: A Remarkably Reusable and Robust Heterogeneous Catalyst for Suzuki–Miyaura and Mizoroki–Heck Cross-Coupling Reactions

, 2018
Pd/Fe-catalyzed Mizoroki–Heck and Suzuki–Miyaura cross-coupling reactions are among the important C–C bond-forming reactions. In the present work, new approaches were evaluated systematically for preparing heterogeneous Pd-based catalysts with high ...
Hamid Asiabi, Y. Yamini, Maryam Shamsayei, Maryam Kazemi Miraki, A. Heydari   +4 more
semanticscholar   +1 more source

Macrophage Activating Properties of The Tryptophan Catabolite Picolinic Acid

2003
Recent studies have suggested a role for aminoacid catabolites as important regulators of macrophage (Mphi) activities. We reported previously that picolinic acid (PA), a tryptophan catabolite produced under inflammatory conditions and a costimulus with IFNgamma of Mphi effector functions, is a selective inducer of the Mphi inflammatory protein-1alpha (
Annamaria Rapisarda, Stefano Massazza, Gioia Reffo, Sandra Pastorino, Luigi Varesio, Maria Carla Bosco   +5 more
openaire   +2 more sources

Is picolinic acid a glycine agonist at strychnine-sensitive receptors?

Brain Research, 1990
By means of unit recording and electrophoretic application, the effect of picolinic acid on feline spinal interneurons in situ was studied in comparison with glycine. Picolinic acid inhibited neuronal firing in 60% of neurons and in some cases the inhibitory actions were antagonized by strychnine.
Nobuyoshi Iwata, Toshiyuki Tonohiro, Mitsuo Tanabe, Tsugio Kaneko   +3 more
openaire   +3 more sources