Results 51 to 60 of about 329 (142)

In Silico Investigation of Potential PARP‐1 Inhibitors from Traditional Chinese Medicine

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2014, Issue 1, 2014., 2014
Poly(ADP‐ribose) polymerases (PARPs) are nuclear enzymes which catalyze the poly‐ADP‐ribosylation involved in gene transcription, DNA damage repair, and cell‐death signaling. As PARP‐1 protein contains a DNA‐binding domain, which can bind to DNA strand breaks and repair the damaged DNA over a low basal level, the inhibitors of poly(ADP‐ribose ...
Kuan-Chung Chen   +3 more
wiley   +1 more source

Tobacco Mosaic Virus (TMV) Inhibitors from Picrasma quassioides Benn [PDF]

open access: yes, 2016
To investigate natural inhibitors against tobacco mosaic virus (TMV) from plants, 10 known β-carboline alkaloids and one quassinoid have been isolated from MeOH extract of the wood of Picrasma quassioides Benn.
Zhong-Kai Zhang (1903414)   +7 more
core   +1 more source

Inhibitory Activities of Cudrania tricuspidata Leaves on Pancreatic Lipase In Vitro and Lipolysis In Vivo

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2012, Issue 1, 2012., 2012
To identify effective herb to treat obesity, we screened 115 herbal extracts for inhibition of porcine pancreatic lipase (triacylg‐ycerol acylhydrolase, EC 3.1.1.3) activity in vitro. Of the extracts tested, Cudrania tricuspidata leaves exhibited the most pronounced inhibitory effect on lipase activity with an IC50 value of 9.91 μg/mL.
Young Sook Kim   +11 more
wiley   +1 more source

Natural Pesticides in Crop Protection: Comparative Advantages, Ecological Risks, and Future Directions

open access: yesJournal of Chemistry, Volume 2026, Issue 1, 2026.
Although synthetic pesticides have long been used to protect crops, their widespread use has led to significant health and environmental problems, including ecological contamination, resistant pest populations, and hazardous residues in food. These restrictions have sparked interest in natural pesticides (NPs), particularly the secondary metabolites of
Ruth Mwangi   +2 more
wiley   +1 more source

Picrasidine I Regulates Apoptosis in Melanoma Cell Lines by Activating ERK and JNK Pathways and Suppressing AKT Signaling

open access: yesEnvironmental Toxicology, Volume 39, Issue 12, Page 5309-5320, December 2024.
ABSTRACT World Health Organization data indicate a continuous increase in melanoma incidence, with metastatic melanoma characterized by poor prognosis and drug resistance. The exploration of therapeutics derived from natural products remains an active area of in vitro research. The aim of this study was to determine the antitumor effects of picrasidine
Mu‐Kuei Shieu   +5 more
wiley   +1 more source

Quassinoids with Insecticidal Activity against Diaphorina citri Kuwayama and Neuroprotective Activities from Picrasma quassioides [PDF]

open access: yes, 2019
Six new quassinoids, named kumulactone F (1), kumulactone G (2), kumulactone H (4), kumulactone I (5), kumulactone J (6), and kumulactone K (7), a pair of undescribed epimers α- and β-nigakihemiacetal G (3), 15 known quassinoids (8–22), and a mixture of ...
Hengshan Wang (680415)   +11 more
core   +1 more source

Inhibitory effects of Picrasma quassioides (D.Don) Benn. on airway inflammation in a murine model of allergic asthma [PDF]

open access: yes, 2014
Picrasma quassioides (D.Don) Benn. (PQ) is used in traditional medicine for the treatment of inflammatory conditions, including gastritis. This study aimed to evaluate the inhibitory effects of PQ on the inflammatory responses in mice with allergic ...
Na Rae Shin   +6 more
core   +1 more source

(±)-Quassidines I and J, Two Pairs of Cytotoxic Bis-β-carboline Alkaloid Enantiomers from Picrasma quassioides [PDF]

open access: yes, 2016
(±)-Quassidines I (1) and J (2), two pairs of new bis-β-carboline alkaloid enantiomers, were isolated from the stems of Picrasma quassioides. Their structures were determined by the analysis of spectroscopic data, including HRESIMS and 2D NMR, and ...
Hao-Bing Yu (1596820)   +10 more
core   +1 more source

Calophya nigra Kuwayama 1908 [PDF]

open access: yes, 2022
Calophya nigra Kuwayama, 1908 (Figs. 21–22) Calophya nigra Kuwayama, 1908: 160. Calophya viridis Kuwayama, 1908: 159; synonymised with Calophya nigra by Miyatake (1992: 19).
Cho, Geonho   +2 more
core   +1 more source

Calophya shinjii Sasaki 1954 [PDF]

open access: yes, 2022
Calophya shinjii Sasaki, 1954 (Figs. 29–31) Calophya shinjii Sasaki, 1954: 31; replacement name for Psylla sorbii Shinji, 1944: 448, nec Psylla sorbi (Linnaeus, 1767): 738; secondary homonym. Distribution in Korea.
Cho, Geonho   +2 more
core   +1 more source

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