Results 61 to 70 of about 329,302 (315)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Aerial view of Drouin, Victoria, during World War II [3] [picture]
, 1944 Title devised by cataloguer from caption on verso.; Condition: Good.; Part of the collection: Drouin town and rural life during World War II.; Inscriptions: "Melbourne 'Argus' Picture" --In pencil on reverse.
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Aerial view of Drouin, Victoria, during World War II [1] [picture]
, 1944 Title devised by cataloguer from caption on verso.; Condition: Good.; Part of the collection: Drouin town and rural life during World War II.; Inscriptions: "Melbourne 'Argus' Picture" --In pencil on reverse.
core
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Anthropocentric principle of modern linguistics and the concept of a picture of the world
Филологический класс, 2004 The author of the article discusses a change in the scientific paradigm in linguistics at the end of the 20th century and how the metamorphoses turned out.
doaj
Differences of kindergarten children's linguistic picture of the world: focus on Hungary, Russia, and Laos. [PDF]
Heliyon, 2021 Lenart I, Markovina I.
europepmc +1 more source
Callistemon lanceolatus DC [picture] /
, 1900 Inscriptions: title below image, "F.P. Nodder pinxit 1777." -- lower left.; Plate 108 of Illustrations of the botany of Captain Cook's voyage round the world in H.M.S.
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source