Results 221 to 230 of about 36,902 (282)

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

Genes causative of primary immunodeficiency are risk factors for and are over-expressed in systemic lupus erythematosus. [PDF]

open access: yesFront Immunol
Davis H   +9 more
europepmc   +1 more source

Traditional Indigenous foodways and retail subsidies: Evidence from the Northwest Territories Community Survey and Nutrition North Canada

open access: yesCanadian Journal of Economics/Revue canadienne d'économique, EarlyView.
Abstract Traditional foods (often referred to as “country foods”) play a critical role in Indigenous culture, nutrition, food sovereignty and food security. Policies that prioritize store‐bought food are often viewed as undermining these foods. We provide evidence that two recent policy reforms that subsidize store‐bought food in the Northwest ...
Bela Georgiev, Nicholas Li
wiley   +1 more source

Association of maternal immunoglobulin G levels with pregnancy outcomes in primary immunodeficiency: A retrospective single-center study. [PDF]

open access: yesMedicine (Baltimore)
Gerek ME   +9 more
europepmc   +1 more source

Digital Professional Practice, Digital Competences and Impact on Family Support Services

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT Digital‐mediated practices in public social services require new strategies for administration, communication, assessment and intervention. Within this field, research framed under UNESCO's (2020) Media and Information Literacy model—examining digital media management and digital competence in information management, communication, digital ...
Guacimara Rodríguez   +6 more
wiley   +1 more source

Anemia‐associated mutations disrupt the CDIN1‐Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA‐I) disease

open access: yesThe FEBS Journal, EarlyView.
Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal   +8 more
wiley   +1 more source

Demonstration of an instream flow model to accommodate a threatened tiger beetle in riverine dune habitat

open access: yesInsect Conservation and Diversity, EarlyView.
Burrows of the threatened Gibson's Big Sand Tiger Beetle in riverine dune habitats are susceptible to flooding through managed flows. HEC‐RAS modelling identified the flow thresholds above which flooding would occur for burrows and affect the beetle larvae. These findings provide instream flow guidelines for conserving this threatened species and guide
Iain D. Phillips   +2 more
wiley   +1 more source

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