Results 31 to 40 of about 241,000 (259)

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari   +10 more
wiley   +1 more source

LA FINANCIACIÓN DE LOS SERVICIOS PÚBLICOS LOCALES EN MUNICIPIOS DESPOBLADOS Y LA REVISIÓN DEL SISTEMA DE PARTICIPACIÓN DE LAS ENTIDADES LOCALES EN LOS TRIBUTOS DEL ESTADO Y DE LAS COMUNIDADES AUTÓNOMAS

open access: yesCrónica Tributaria
La Constitución Española consagra un sistema de financiación local basado en tres pilares: los tributos propios, la participación en los tributos del Estado y de las comunidades autónomas.
Sedeño López, José Francisco
doaj   +1 more source

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

open access: yesAdvanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang   +11 more
wiley   +1 more source

Estudio prospectivo de cirugía de hallux valgus con técnica de Bosch y técnica MICA.

open access: yesRevista de la Asociación Argentina de Ortopedia y Traumatología, 2021
Introducción: Existen múltiples tratamientos quirúrgicos del hallux valgus. El propósito de este estudio fue comparar los resultados radiográficos de corrección angular y su mantenimiento a mediano plazo, entre dos técnicas percutáneas: MICA y Bösch ...
Juan Manuel Yañez Arauz   +6 more
doaj   +1 more source

Defect‐Templated Phase Engineering in Atomically Thin Metals

open access: yesAdvanced Materials, EarlyView.
Graphene defects are transformed from passive imperfections into programmable templates for phase‐selective growth of atomically thin silver. Plasma‐generated boundary defects favor Ag(1), whereas sp3‐rich zero‐layer graphene promotes Ag(2). This defect‐directed intercalation links local graphene chemistry to crystalline phase, electronic structure ...
Arpit Jain   +25 more
wiley   +1 more source

Production of Low Calorie Bakery Product with Pleasant Flavour, Antioxidant and Antimicrobial Activities

open access: yesPolish Journal of Food and Nutrition Sciences, 2014
Aromatic plants are considered sources of antioxidants, antimicrobial and favouring agents. Four aromatic plants (Thymus vulgaris L., Foeniculum vulgare, Pimpinella anisum L. and Trigonellafoenum-graecum L.) were analysed in the study.
Hussein Ahmed M.S.   +3 more
doaj   +1 more source

How “Green” is Your Functional Material? Assessing Environmental Impacts of Multi‐Step Synthetic Protocols in Material Sciences at Various Technology Levels

open access: yesAdvanced Materials, EarlyView.
Environmental Synthesis Radar (ESR) evaluates the environmental impact of (early‐stage) multi‐step chemical syntheses, providing a holistic view by using 18 midpoint impact categories. Unlike conventional life‐cycle assessment (LCA) approaches, ESR reveals three complementary metrics: overall impact Vtotal, environmental hotspots VEF, and critical ...
Laura Plein   +8 more
wiley   +1 more source

Manejo quirúrgico del hallux valgus

open access: yesRevista Colombiana de Ortopedia y Traumatología, 2019
El hallux valgus es una patología muy común en nuestra población, la decisión quirúrgica se basa en la sintomatología de los pacientes y nunca se realiza una corrección por estética.
Jose Roberto Lopez-Cadavid   +7 more
doaj  

Resultados funcionales del tratamiento de coaliciones calcáneo-escafoideas con resección e interposición de grasa autóloga: Experiencia de dos centros

open access: yesRevista de la Asociación Argentina de Ortopedia y Traumatología, 2021
Objetivo: Evaluar los resultados clínico-radiográficos y las complicaciones en pacientes
Julio Javier Masquijo   +4 more
doaj   +1 more source

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